Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.62 |
| ▸ | RXRA | P19793 | 6/20 | 0.61 |
| ▸ | RXRG | P48443 | 6/20 | 0.61 |
| ▸ | MMP12 | P39900 | 1/20 | 0.58 |
| ▸ | MMP13 | P45452 | 1/20 | 0.58 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.56 |
| ▸ | MMP2 | P08253 | 1/20 | 0.56 |
| ▸ | RXRB | P28702 | 5/20 | 0.55 |
| ▸ | MMP3 | P08254 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.47 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL335492 | 0.94 | CTBP2 (0.62) | HTTTSHRABCC4LMNAGAA | |
| Hydrochloric Acid SCHEMBL7981327 | 0.92 | CTBP2 (0.61) | HTTTSHRABCC4LMNAGAA | |
| SCHEMBL29236556 | 0.92 | CTBP2 (0.61) | HTTTSHRABCC4LMNAGAA | |
| SCHEMBL6917099 | 0.84 | SRD5A2 (0.57) | HTTLMNARXRARXRGCTBP2 | |
| SCHEMBL6540182 | 0.84 | MAOB (0.56) | HTTTSHRABCC4LMNAGAA | |
| SCHEMBL18427891 | 0.83 | LMNA (0.86) | HTTTSHRABCC4LMNAGAA | |
| SCHEMBL68027 | 0.83 | LMNA (0.86) | HTTTSHRABCC4LMNAGAA | |
| SCHEMBL23972420 | 0.83 | GRIN2D (0.54) | HTTTSHRABCC4LMNAGAA | |
| SCHEMBL31226109 | 0.83 | MMP12 (0.64) | HTTTSHRABCC4LMNAGAA | |
| SCHEMBL6937899 | 0.79 | CTBP2 (0.59) | HTTMMP12MMP13CTBP2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6048854-A | ANTICOAGULANTS; ANTICANCER AGENT; WOUND HEALING AGENTS;BONE DISORDERS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2000-04-11 | — | — | US | disclosed |
| US-5707994-A | USEFUL AS A PLATELET AGGREGATION INHIBITOR, CANCER METASTASIS INHIBITOR, WOUND HEALING AGENT OR A BONE RESORPTION INHIBITOR | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-01-13 | — | — | US | disclosed |
| EP-0725059-A1 | 2,3-DIAMINOPROPIONIC ACID DERIVATIVE | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1996-08-07 | — | — | EP | disclosed |