Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CXCR2 | P25025 | 4/20 | 0.44 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL144190 | 0.83 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2HPGDGPR35TP53 | |
| Bromide SCHEMBL8457695 | 0.81 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2HPGDGPR35TP53 | |
| SCHEMBL8548763 | 0.77 | PTPRC (0.46) | ALDH1A1HTTSMN1; SMN2HPGDGPR35 | |
| Bromide SCHEMBL8185078 | 0.76 | ALDH1A1 (0.44) | ALDH1A1HTTSMN1; SMN2HPGDGPR35 | |
| SCHEMBL4435513 | 0.74 | TDP1 (0.54) | ALDH1A1HTTSMN1; SMN2HPGDGPR35 | |
| SCHEMBL10485916 | 0.70 | CA12 (0.47) | ALDH1A1SMN1; SMN2HPGDMAPK1MEN1 | |
| SCHEMBL4402148 | 0.70 | ITGA4 (0.51) | ALDH1A1HTTSMN1; SMN2HPGDGPR35 | |
| SCHEMBL10577600 | 0.69 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2HPGDGPR35TP53 | |
| SCHEMBL27525369 | 0.69 | ALDH1A1 (0.53) | ALDH1A1HTTSMN1; SMN2HPGDGPR35 | |
| SCHEMBL28981557 | 0.69 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2HPGDGPR35TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143772-A | ANTIDEPRESSANTS AND TRANQUILIZERS FORMED FROM REACTION OF BORON TRIBROMIDE AND CARBAMYL SUBSTITUTED BENZOFURAN | SYNTHELABO (FR) | 2000-11-07 | — | — | US | disclosed |