SCHEMBL144190

SCHEMBL144190

O=[N+]([O-])c1ccc(O)c(Br)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.62
TSHR P16473 3/20 0.62
GPR35 Q9HC97 2/20 0.62
TP53 P04637 1/20 0.62
HPGD P15428 1/20 0.62
MAPK1 P28482 1/20 0.62
SMN1; SMN2 Q16637 1/20 0.62
GAA P10253 1/20 0.60
THRB P10828 1/20 0.60
ERN1 O75460 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.50
TDP1 Q9NUW8 3/20 0.49
CXCR2 P25025 2/20 0.49
MEN1 O00255 1/20 0.49
CXCR1 P25024 1/20 0.49
KMT2A Q03164 1/20 0.49
HDAC6 Q9UBN7 1/20 0.49
HSP90AA1 P07900 1/20 0.49
ALOX15 P16050 2/20 0.48
HIF1A Q16665 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL8457695 0.98 ALDH1A1 (0.60) ALDH1A1TSHRGPR35TP53HPGD
SCHEMBL4435513 0.85 TDP1 (0.54) ALDH1A1TSHRGPR35TP53HPGD
SCHEMBL526702 0.83 GPR35 (0.62) ALDH1A1TSHRGPR35TP53HPGD
SCHEMBL8185359 0.83 ALDH1A1 (0.48) ALDH1A1TSHRGPR35TP53HPGD
SCHEMBL27284850 0.81 ALDH1A1 (0.64) ALDH1A1TSHRGPR35TP53HPGD
SCHEMBL27712689 0.81 HSPB1 (0.53) ALDH1A1TSHRGPR35TP53HPGD
4-Nitrocatechol SCHEMBL156909 0.80 TSHR (0.69) ALDH1A1TSHRGPR35TP53HPGD
4-Nitrocatechol SCHEMBL1608536 0.80 TSHR (0.69) ALDH1A1TSHRGPR35TP53HPGD
4-Nitrocatechol SCHEMBL11765698 0.80 TSHR (0.69) ALDH1A1TSHRGPR35TP53HPGD
SCHEMBL30317899 0.80 PTPRC (0.54) ALDH1A1TSHRGPR35TP53HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 343 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120004758-A Screening and verifying method of targeting sclerostin specific structural domain small molecule inhibitor 中山大学 2025-05-16 CN claimed
CN-118549570-A Detection method of 13 disinfection byproducts in sediment 上海市环境科学研究院 2024-08-27 CN claimed
CN-114113370-B Analysis method of aromatic halogenated disinfection byproducts in water 东南大学 2024-03-26 CN claimed
CN-115920972-A Synthetic method and application of high-efficiency catalytic reduction nitroaromatic catalytic material 南京师范大学 2023-04-07 CN claimed
CN-114113370-A Analysis method of aromatic halogenated disinfection byproducts in water 东南大学 2022-03-01 CN claimed
CN-107954878-A A kind of synthetic method of intermediate 3- fluoro-4-nitrophenols 苏州艾缇克药物化学有限公司 2018-04-24 CN claimed
CN-102173992-A Preparation method of nitrophenol compounds UNIV NANTONG 2011-09-07 CN claimed
EP-4748837-A1 AROMATIC AMIDE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF Zhejiang Hisun Pharmaceutical Co., Ltd. (CN) 2026-05-27 EP disclosed
CN-121759215-B Fluorescent composite material, preparation method thereof and application thereof in formaldehyde detection 德州学院 2026-05-19 CN disclosed
CN-121718348-B Fluorescent composite nano material for detecting formaldehyde and preparation method and application thereof 德州学院 2026-05-12 CN disclosed
US-20260085048-A1 ACSS2 INHIBITORS AND METHODS OF USE THEREOF EPIVARIO INC (US) 2026-03-26 US disclosed
US-20260043056-A1 REDUCTION OF NITROGEN-CONTAINING GROUPS IN A TARGET COMPOUND USING A BIOCATALYST UNIV OXFORD INNOVATION LTD (GB) 2026-02-12 US disclosed
US-20260028316-A1 Biphenyl and Phenylpyridine Compounds PFIZER INC. (US) 2026-01-29 US disclosed
US-4983512-A HALONITROPHENYLPHOSPHORIC ACID; DIAGNOSIS OF PROSTATE DISEASES TOYO BOSEKI KABUSHIKI KAISHA (JP) 1991-01-08 US disclosed
EP-0346912-A2 Sugar ester derivatives, reagents for measurement of hydrolase activity and methods for measurement of hydrolase activity Toyo Boseki Kabushiki Kaisha (JP) 1989-12-20 EP disclosed
EP-0319993-A2 Maltooligosaccharide derivatives and reagents for determination of amylase activity Toyo Boseki Kabushiki Kaisha (JP) 1989-06-14 EP disclosed
EP-0153642-A2 Process for the preparation of monomeric aromatic hydroxyurethanes BAYER AG (DE) 1985-09-04 EP disclosed
US-4447260-A N-Substituted phenyl-1-methylcyclopropanecarboxamides, and their herbicidal use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-05-08 US disclosed
US-4347387-A ISOMERIZATION OF 7-HYDROXYGERANYLAMINES OR 7-HYDROXYNERYLAMINES, PALLADIUM-PHOSPHINE CATALYST, ACIDOLYSIS TAKASAGO PERFUMERY CO., LTD. (JP) 1982-08-31 US disclosed
US-4005150-A Phenyl ethers having juvenile hormone activity CESKOSLOVENSKA AKADEMIE VED (CS) 1977-01-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260043056-A1 REDUCTION OF NITROGEN-CONTAINING GROUPS IN A TARGET COMPOUND USING A BIOCATALYST NOS3, MPO, NOS2 ALDH1A1 4264/4885TSHR 3943/4885GPR35 4546/4885
US-20260028316-A1 Biphenyl and Phenylpyridine Compounds KAT2B, KAT2A, KAT6A ALDH1A1 1348/4885TSHR 2742/4885GPR35 1516/4885
US-20260085048-A1 ACSS2 INHIBITORS AND METHODS OF USE THEREOF ACSS2, GLS2, ACSL3 ALDH1A1 1031/4885TSHR 1970/4885GPR35 2558/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.