Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.57 |
| ▸ | MEN1 | O00255 | 8/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL965515 | 0.87 | LMNA (0.62) | KMT2AMEN1ALDH1A1MAPTHTT | |
| SCHEMBL16112188 | 0.85 | LMNA (0.55) | KMT2AMEN1ALDH1A1MAPTHTT | |
| SCHEMBL1222109 | 0.84 | MEN1 (0.52) | KMT2AMEN1ALDH1A1MAPTHTT | |
| SCHEMBL22789557 | 0.84 | MEN1 (0.53) | KMT2AMEN1ALDH1A1MAPTHTT | |
| SCHEMBL23986656 | 0.84 | ALDH1A1 (0.66) | KMT2AMEN1ALDH1A1MAPTHTT | |
| SCHEMBL7845532 | 0.84 | MEN1 (0.52) | KMT2AMEN1ALDH1A1MAPTHTT | |
| SCHEMBL22309108 | 0.84 | MEN1 (0.68) | KMT2AMEN1ALDH1A1MAPTHTT | |
| SCHEMBL8878617 | 0.83 | KMT2A (0.65) | KMT2AMEN1ALDH1A1L3MBTL1LMNA | |
| SCHEMBL3355644 | 0.83 | KMT2A (0.52) | KMT2AMEN1ALDH1A1L3MBTL1LMNA | |
| SCHEMBL15549442 | 0.83 | FPR2 (0.53) | KMT2AMEN1ALDH1A1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1047673-A1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 2000-11-02 | — | — | EP | disclosed |
| US-6048856-A | ANALGESICS; ANTIINFLAMMATORY AGENTS | NOVO NORDISK A/S (DK) | 2000-04-11 | — | — | US | disclosed |
| WO-1999031058-A1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1999-06-24 | — | — | WO | disclosed |