Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.34 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
| ▸ | PLK1 | P53350 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13428541 | 0.80 | SSTR3 (0.35) | P2RX3GSTP1GSTM2MAPTTGFBR1 | |
| SCHEMBL8183546 | 0.74 | KMT2A (0.37) | MAPTTGFBR1KMT2AHDAC1 | |
| SCHEMBL8185667 | 0.72 | P2RX3 (0.35) | P2RX3GSTP1GSTM2TGFBR1ALDH1A1 | |
| SCHEMBL8182903 | 0.72 | KDM4E (0.37) | P2RX3MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL8173598 | 0.71 | TGFBR1 (0.35) | P2RX3TGFBR1 | |
| SCHEMBL8182243 | 0.71 | MAPT (0.38) | MAPTALDH1A1LMNAKMT2AHDAC1 | |
| SCHEMBL8189381 | 0.71 | ALDH1A1 (0.35) | TGFBR1ALDH1A1LMNAKMT2AHDAC1 | |
| SCHEMBL13428496 | 0.69 | NR1H4 (0.34) | P2RX3MAPTTGFBR1ALDH1A1LMNA | |
| SCHEMBL4225299 | 0.69 | CDK12 (0.40) | — | |
| SCHEMBL4225295 | 0.69 | CDK12 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008075757-A1 | N-HYDROXYACRYLAMIDE COMPOUNDS | ASTELLAS PHARMA INC. (JP) | 2008-06-26 | — | — | WO | disclosed |