Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 3/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | CHI3L1 | P36222 | 1/20 | 0.46 |
| ▸ | MC4R | P32245 | 2/20 | 0.44 |
| ▸ | MC3R | P41968 | 2/20 | 0.44 |
| ▸ | MC1R | Q01726 | 2/20 | 0.44 |
| ▸ | GBA1 | P04062 | 2/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CHIT1 | Q13231 | 1/20 | 0.41 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8177314 | 0.95 | AGTR2 (0.49) | AGTR2SLC6A2SLC6A4SLC6A3CHI3L1 | |
| SCHEMBL3724429 | 0.90 | SLC6A2 (0.50) | AGTR2SLC6A2SLC6A4SLC6A3CHI3L1 | |
| SCHEMBL4237634 | 0.90 | SLC6A2 (0.50) | AGTR2SLC6A2SLC6A4SLC6A3CHI3L1 | |
| SCHEMBL18258630 | 0.85 | CHI3L1 (0.52) | AGTR2CHI3L1MC4RMC3RMC1R | |
| SCHEMBL29729985 | 0.82 | GBA1 (0.50) | AGTR2SLC6A2SLC6A4SLC6A3CHI3L1 | |
| SCHEMBL8791548 | 0.75 | HSD11B1 (0.44) | AGTR2CHI3L1MC4RMC3RMC1R | |
| SCHEMBL5193918 | 0.74 | HTR3A (0.40) | SLC6A2SLC6A4SLC6A3CHI3L1KCNH2 | |
| SCHEMBL18608060 | 0.72 | CHI3L1 (0.58) | SLC6A3CHI3L1KCNH2CHIT1CHIA | |
| SCHEMBL9727457 | 0.72 | SLC6A2 (0.54) | AGTR2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL18589457 | 0.72 | CHI3L1 (0.58) | SLC6A3CHI3L1KCNH2CHIT1CHIA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000063168-A1 | SYNTHESIS OF AZETIDINE DERIVATIVES | COELACANTH CHEMICAL CORPORATION (US) | 2000-10-26 | — | — | WO | disclosed |