Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9792994 | 0.84 | MME (0.39) | MMEACEALDH1A1 | |
| SCHEMBL18113296 | 0.83 | ALDH1A1 (0.37) | ALDH1A1LMNAHSD17B10CYP3A4CYP2C19 | |
| SCHEMBL6229414 | 0.81 | MME (0.46) | MMEACE | |
| SCHEMBL11003404 | 0.81 | MME (0.46) | MMEACE | |
| SCHEMBL9089035 | 0.81 | MME (0.46) | MMEACE | |
| SCHEMBL31065468 | 0.80 | METAP2 (0.42) | ALDH1A1LMNAHSD17B10CYP3A4CYP2C19 | |
| SCHEMBL12707543 | 0.80 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10CYP3A4CYP2C19 | |
| SCHEMBL12707546 | 0.80 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10CYP3A4CYP2C19 | |
| SCHEMBL16626926 | 0.80 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10CYP3A4CYP2C19 | |
| SCHEMBL10826684 | 0.80 | MME (0.42) | MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10011668-B2 | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2018-07-03 | — | — | US | disclosed |
| US-20180057622-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2018-03-01 | — | — | US | disclosed |
| EP-2334201-B1 | THIOL-CONTAINING FRAGRANCE AND FLAVOR MATERIALS | TAKASAGO PERFUMERY CO LTD (JP) | 2016-07-27 | — | — | EP | disclosed |
| US-8536364-B2 | Method for producing sulfur-containing carboxylic acid esters | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2013-09-17 | — | — | US | disclosed |
| US-8445051-B2 | Thiol-containing fragrance and flavor materials | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2013-05-21 | — | — | US | disclosed |
| EP-2452933-A1 | Method for producing sulfur-containing carboxylic acid esters | Takasago International Corporation (JP) | 2012-05-16 | — | — | EP | disclosed |
| US-20110282089-A1 | METHOD FOR PRODUCING SULFUR-CONTAINING CARBOXYLIC ACID ESTERS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-11-17 | — | — | US | disclosed |
| US-20110256071-A1 | THIOL-CONTAINING FRAGRANCE AND FLAVOR MATERIALS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-10-20 | — | — | US | disclosed |
| CN-102176838-A | Thiol-containing fragrances and flavorings | TAKASAGO PERFUMERY CO LTD | 2011-09-07 | — | — | CN | disclosed |
| EP-2334201-A1 | THIOL-CONTAINING FRAGRANCE AND FLAVOR MATERIALS | Takasago International Corporation (JP) | 2011-06-22 | — | — | EP | disclosed |
| US-5856322-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS, CARDIOVASCULAR DISORDERS | MERCK FROSST CANADA, INC. (CA) | 1999-01-05 | — | — | US | disclosed |
| EP-0480717-B1 | Unsaturated hydroxyalkylquinoline acids as leukotriene antagonists | MERCK FROSST CANADA INC (CA) | 1998-04-15 | — | — | EP | disclosed |
| US-5565473-A | USEFUL AS ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY AND CYTOPROTECTIVE AGENTS; MONTELUKAST AND ITS SODIUM SALT | MERCK FROSST CANADA, INC. (CA) | 1996-10-15 | — | — | US | disclosed |
| EP-0480708-B1 | Hydroxyalkylquinoline ether acids as leukotriene antagonists | MERCK FROSST CANADA INC (CA) | 1995-10-11 | — | — | EP | disclosed |
| US-5428033-A | Useful as anti-asthmatic, anti-allergic, anti-inflammatory and cytoprotecyive agents | MERCK FROSST CANADA, INC. (CA) | 1995-06-27 | — | — | US | disclosed |
| US-5270324-A | Fluorinated hydroxyalkylquinoline acids as leukotriene antagonists | MERCK FROSST CANADA, INC. (CA) | 1993-12-14 | — | — | US | disclosed |
| US-5266568-A | Hydroxyalkylquinoline ether acids as leukotriene antagonists | MERCK FROSST CANADA, INC. (CA) | 1993-11-30 | — | — | US | disclosed |
| EP-0480716-A1 | Saturated hydroxyalkylquinoline acids as leukotriene antagonists | MERCK FROSST CANADA INC. (CA) | 1992-04-15 | — | — | EP | disclosed |
| EP-0480717-A1 | Unsaturated hydroxyalkylquinoline acids as leukotriene antagonists | MERCK FROSST CANADA INC. (CA) | 1992-04-15 | — | — | EP | disclosed |
| EP-0480708-A2 | Hydroxyalkylquinoline ether acids as leukotriene antagonists | MERCK FROSST CANADA INC. (CA) | 1992-04-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110256071-A1 | THIOL-CONTAINING FRAGRANCE AND FLAVOR MATERIALS | TAS1R1, TAS2R1, TAS2R5 | MME 4595/4885ACE 3926/4885ALDH1A1 29/4885 |
| US-20110282089-A1 | METHOD FOR PRODUCING SULFUR-CONTAINING CARBOXYLIC ACID ESTERS | CBR3, ALDH18A1, TAS2R3 | MME 4681/4885ACE 4002/4885ALDH1A1 37/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.