SCHEMBL819063

SCHEMBL819063

CC(C)COCC(C(=O)Cl)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.43
ALDH1A1 P00352 2/20 0.42
TSHR P16473 1/20 0.42
GPR88 Q9GZN0 1/20 0.40
KDM4E B2RXH2 1/20 0.40
LMNA P02545 2/20 0.39
HTT P42858 1/20 0.38
GAA P10253 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2D6 P10635 1/20 0.38
PKM P14618 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
CYP2C19 P33261 1/20 0.38
EPHX1 P07099 1/20 0.38
MAPT P10636 1/20 0.38
HSD17B10 Q99714 1/20 0.37
CRHBP P24387 1/20 0.37
CRHR2 Q13324 1/20 0.37
KCNQ2 O43526 1/20 0.37
KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL818912 0.85 GAA (0.43) NPSR1ALDH1A1TSHRKDM4ELMNA
SCHEMBL819824 0.81 GLS (0.46) NPSR1ALDH1A1TSHRLMNACYP1A2
SCHEMBL888482 0.81 MMP8 (0.48) NPSR1ALDH1A1TSHRKDM4EGAA
SCHEMBL27774147 0.79 LMNA (0.50) ALDH1A1LMNACYP2C19EPHX1HSD17B10
Bicarbonate SCHEMBL28037193 0.79 ALDH1A1 (0.47) NPSR1ALDH1A1TSHRGPR88KDM4E
SCHEMBL22418886 0.78 GLS (0.46) NPSR1ALDH1A1KDM4ELMNAGAA
SCHEMBL13658246 0.77 POLB (0.50) ALDH1A1LMNASMN1; SMN2CYP2C19EPHX1
Diphenylacetic Acid SCHEMBL27391525 0.77 ALDH1A1 (0.46) NPSR1ALDH1A1TSHRKDM4ELMNA
SCHEMBL12496426 0.76 LMNA (0.48) ALDH1A1TSHRGPR88KDM4ELMNA
SCHEMBL27769332 0.75 LMNA (0.43) NPSR1KDM4ELMNAHTTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102250266-B Process for producing solid catalyst component for olefin polymerization SUMITOMO CHEMICAL CO., LTD. (JP) 2014-10-22 CN disclosed
CN-103289210-A Polypropylene resin composition and molded body containing same SUMITOMO CHEMICAL CO 2013-09-11 CN disclosed
US-8288488-B2 Process for producing solid catalyst component for olefin polymerization SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-16 US disclosed
CN-102250266-A Process for producing solid catalyst component for olefin polymerization SUMITOMO CHEMICAL CO 2011-11-23 CN disclosed
US-20110269929-A1 PROCESS FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-11-03 US disclosed
US-20110269928-A1 PROCESS FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-11-03 US disclosed