Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 7/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | GCGR | P47871 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8190757 | 1.00 | HIF1A (0.41) | HIF1AMAPK14PTPN2PTPN1PTPN11 | |
| SCHEMBL8196227 | 0.92 | HIF1A (0.36) | HIF1AMAPK14PTPN2PTPN1PTPN11 | |
| SCHEMBL8180157 | 0.86 | HIF1A (0.40) | HIF1AMAPK14PTPN2PTPN1PTPN11 | |
| SCHEMBL8180159 | 0.86 | HIF1A (0.40) | HIF1AMAPK14PTPN2PTPN1PTPN11 | |
| SCHEMBL8190761 | 0.83 | MAPK14 (0.36) | HIF1AMAPK14PTPN2PTPN1PTPN11 | |
| SCHEMBL7467255 | 0.78 | HIF1A (0.41) | HIF1AMAPK14PTPN2PTPN1PTPN11 | |
| SCHEMBL7467258 | 0.78 | HIF1A (0.41) | HIF1AMAPK14PTPN2PTPN1PTPN11 | |
| SCHEMBL8544633 | 0.77 | HIF1A (0.44) | HIF1AMAPK14PTPN2PTPN1PTPN11 | |
| SCHEMBL7498154 | 0.77 | HIF1A (0.57) | HIF1AMAPK14RXFP1GCGRCHEK2 | |
| SCHEMBL8196231 | 0.75 | MAPK14 (0.36) | HIF1AMAPK14PTPN2PTPN1PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0984924-A1 | O-BENZYL OXIME ETHER DERIVATIVES AND THEIR USE AS PESTICIDES | Novartis AG (CH) | 2000-03-15 | — | — | EP | disclosed |
| WO-1998054126-A1 | O-BENZYL OXIME ETHER DERIVATIVES AND THEIR USE AS PESTICIDES | NOVARTIS AG (CH) | 1998-12-03 | — | — | WO | disclosed |