Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 3/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 2/20 | 0.32 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | RAF1 | P04049 | 1/20 | 0.31 |
| ▸ | GCGR | P47871 | 1/20 | 0.31 |
| ▸ | PLK4 | O00444 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | LYN | P07948 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8190761 | 0.92 | MAPK14 (0.36) | MAPK14BTKTLR8TLR7CHEK2 | |
| SCHEMBL8196227 | 0.83 | HIF1A (0.36) | MAPK14BTKTLR8TLR7KDR | |
| SCHEMBL8544631 | 0.83 | MAPK14 (0.37) | MAPK14BTKTLR8TLR7KDR | |
| SCHEMBL8180161 | 0.81 | MAPK14 (0.39) | MAPK14BTKTLR8TLR7CHEK2 | |
| SCHEMBL7494028 | 0.77 | MAPK14 (0.39) | MAPK14BTKTLR8TLR7KDR | |
| SCHEMBL7466206 | 0.76 | MAPK14 (0.36) | MAPK14RXFP1PPARGHIF1A | |
| SCHEMBL8190757 | 0.75 | HIF1A (0.41) | MAPK14BTKTLR8TLR7CHEK2 | |
| SCHEMBL8190754 | 0.75 | HIF1A (0.41) | MAPK14BTKTLR8TLR7CHEK2 | |
| SCHEMBL7467262 | 0.75 | MAPK14 (0.39) | MAPK14BTKTLR8TLR7CHEK2 | |
| SCHEMBL8544633 | 0.73 | HIF1A (0.44) | MAPK14BTKTLR8TLR7KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0984924-A1 | O-BENZYL OXIME ETHER DERIVATIVES AND THEIR USE AS PESTICIDES | Novartis AG (CH) | 2000-03-15 | — | — | EP | disclosed |
| WO-1998054126-A1 | O-BENZYL OXIME ETHER DERIVATIVES AND THEIR USE AS PESTICIDES | NOVARTIS AG (CH) | 1998-12-03 | — | — | WO | disclosed |