SCHEMBL8190848

SCHEMBL8190848

O=C1C(O)=C(O)C(=O)c2cc3ccccc3cc21

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APAF1 O14727 1/20 0.64
TDP2 O95551 1/20 0.64
BCL2 P10415 1/20 0.50
MCL1 Q07820 1/20 0.50
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
HDAC4 P56524 1/20 0.42
HDAC2 Q92769 1/20 0.42
HDAC8 Q9BY41 1/20 0.42
CYP1A2 P05177 1/20 0.42
GSTP1 P09211 1/20 0.41
NQO1 P15559 1/20 0.41
MAOA P21397 2/20 0.41
ALDH1A1 P00352 2/20 0.41
HPGD P15428 2/20 0.41
ESR1 P03372 2/20 0.41
ESR2 Q92731 2/20 0.41
TP53 P04637 1/20 0.41
TSHR P16473 1/20 0.41
MAPK1 P28482 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL244695 0.89 APAF1 (0.50) APAF1TDP2BCL2MCL1NPC1
SCHEMBL29488106 0.89 APAF1 (0.50) APAF1TDP2BCL2MCL1NPC1
Hydrochloric Acid SCHEMBL16369796 0.87 APAF1 (0.48) APAF1TDP2BCL2MCL1NPC1
SCHEMBL3465719 0.85 APAF1 (0.46) APAF1TDP2BCL2MCL1NPC1
SCHEMBL11352933 0.85 APAF1 (0.46) APAF1TDP2BCL2MCL1NPC1
SCHEMBL354514 0.84 MEN1 (0.56) APAF1TDP2BCL2MCL1NPC1
SCHEMBL30130196 0.84 MEN1 (0.56) APAF1TDP2BCL2MCL1NPC1
SCHEMBL29364188 0.84 MEN1 (0.56) APAF1TDP2BCL2MCL1NPC1
SCHEMBL16144676 0.81 MEN1 (0.53) APAF1TDP2BCL2MCL1NPC1
SCHEMBL19230417 0.81 ALDH1A1 (0.52) APAF1TDP2BCL2MCL1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0020305-B1 1-HYDROXY-4-HETEROARYLAMINO ANTHRAQUINONE DYESTUFFS, THEIR PREPARATION AND THEIR USE IN DYEING POLYESTERS IN THE MASS CIBA-GEIGY AG (CH) 1982-08-04 EP claimed
CN-106537255-A Anthraquinone Compounds for Color Filters of LCDs 陶氏环球技术有限责任公司 2017-03-22 CN disclosed
CN-105899619-A Anthraquinone dye used for a color filter of an lcd 陶氏环球技术有限责任公司 2016-08-24 CN disclosed
EP-0820498-B1 DEVELOPER SYSTEM FOR BASE REACTABLE PETROLEUM FUEL MARKERS UNITED COLOR MFG INC (US) 2000-06-28 EP disclosed
US-5808154-A Process for the production of an aromatic hydrazo compound TOYO INK MANUFACTURING CO., LTD. (JP) 1998-09-15 US disclosed
EP-0820498-A1 DEVELOPER SYSTEM FOR BASE REACTABLE PETROLEUM FUEL MARKERS United Color Manufacturing Inc. (US) 1998-01-28 EP disclosed
US-5672182-A QUATERNARY ALKYL AMMONIUM BASE AS DEVELOPER AND COLOR OR FLUORESCENT MARKER UNITED COLOR MANUFACTURING INC. (US) 1997-09-30 US disclosed
WO-1996032461-A1 DEVELOPER SYSTEM FOR BASE REACTABLE PETROLEUM FUEL MARKERS UNITED COLOR MANUFACTURING, INC. (US) 1996-10-17 WO disclosed
EP-0391606-B1 Process for the production of an aromatic hydrazo compound TOYO INK MFG CO (JP) 1995-07-05 EP disclosed
EP-0391606-A1 Process for the production of an aromatic hydrazo compound TOYO INK MANUFACTURING CO., LTD. (JP) 1990-10-10 EP disclosed