Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | CTSG | P08311 | 1/20 | 0.32 |
| ▸ | CMA1 | P23946 | 1/20 | 0.32 |
| ▸ | CTRC | Q99895 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4760259 | 0.72 | ALDH1A1 (0.32) | MAPTNPSR1ADRB1ALDH1A1 | |
| SCHEMBL223853 | 0.62 | MAPT (0.42) | MAPTLMNANPSR1TDP1L3MBTL1 | |
| SCHEMBL3414344 | 0.61 | ADRB1 (0.70) | MAPTLMNANPSR1TDP1L3MBTL1 | |
| SCHEMBL10063748 | 0.61 | ADRB1 (0.70) | MAPTLMNANPSR1TDP1L3MBTL1 | |
| SCHEMBL7105773 | 0.61 | ADRB1 (0.70) | MAPTLMNANPSR1TDP1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL820585 | 0.60 | MAPT (0.41) | MAPTLMNANPSR1TDP1L3MBTL1 | |
| SCHEMBL171845 | 0.60 | MAPT (0.63) | MAPTLMNANPSR1TDP1L3MBTL1 | |
| SCHEMBL296284 | 0.60 | MAPT (0.46) | MAPTLMNANPSR1TDP1L3MBTL1 | |
| SCHEMBL8296046 | 0.59 | MAPT (0.41) | MAPTLMNANPSR1TDP1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL34870 | 0.59 | MAPT (0.44) | MAPTLMNANPSR1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2574187-B1 | SQUALANE AND ISOSQUALANE COMPOSITIONS AND METHODS FOR PREPARING THE SAME | AMYRIS INC (US) | 2019-09-11 | — | — | EP | disclosed |
| US-8586814-B2 | Squalane and isosqualane compositions and methods for preparing the same | Amyris, Inc. (US) | 2013-11-19 | — | — | US | disclosed |
| EP-2574187-A1 | SQUALANE AND ISOSQUALANE COMPOSITIONS AND METHODS FOR PREPARING THE SAME | Amyris Biotechnologies, Inc. (US) | 2013-04-03 | — | — | EP | disclosed |
| WO-2011146837-A1 | SQUALANE AND ISOSQUALANE COMPOSITIONS AND METHODS FOR PREPARING THE SAME | Amyris, Inc. (US) | 2011-11-24 | — | — | WO | disclosed |
| US-20110287988-A1 | SQUALANE AND ISOSQUALANE COMPOSITIONS AND METHODS FOR PREPARING THE SAME | EUAGORE, LLC | 2011-11-24 | — | — | US | disclosed |
| US-7964758-B2 | Process for production of 2-(substituted phenyl)-3,3,3-trifluoropropene compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2011-06-21 | — | — | US | disclosed |
| US-20100160683-A1 | Process for Production of 2-(Substituted Phenyl)-3,3,3-Trifluoropropene Compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-06-24 | — | — | US | disclosed |
| US-6403802-B1 | MIXING IN LIQUID MEDIUM STRONG BASE, ARYL HALIDE OR ARYL PSEUDOHALIDE, PRIMARY AND/OR SECONDARY AMINE, NICKEL, PALLADIUM OR PLATINUM COMPOUND, N-HETEROCYCLIC CARBENE SUCH AS IMIDAZOLINE-2-YLIDENE, BIS(IMIDAZOLINE-2-YLIDENE) OR SALTS | UNIVERSITY OF NEW ORLEANS RESEARCH & TECHNOLOGY FOUNDATION | 2002-06-11 | — | — | US | disclosed |
| US-6316380-B1 | ONE TRANSITION METAL COMPOUND AND AT LEAST ONE N-HETEROCYCLIC CARBENE OR ITS PROTONATED SALT | UNIVERSITY OF NEW ORLEANS RESEARCH & TECHNOLOGY FOUNDATION | 2001-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110287988-A1 | SQUALANE AND ISOSQUALANE COMPOSITIONS AND METHODS FOR PREPARING THE SAME | SQLE, FDFT1, COASY | ACHE 63/4885MAPT 3566/4885LMNA 1601/4885 |
| US-20100160683-A1 | Process for Production of 2-(Substituted Phenyl)-3,3,3-Trifluoropropene Compound | PEX3, SCO2, LPO | ACHE 4021/4885MAPT 4565/4885LMNA 3299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.