Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 5/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 3/20 | 0.45 |
| ▸ | HTR6 | P50406 | 3/20 | 0.43 |
| ▸ | HTR3A | P46098 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR5A | P47898 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL15937978 | 0.98 | LMNA (0.48) | HTR1AADRB1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29915638 | 0.84 | ADRB1 (0.41) | HTR1AADRB1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1441614 | 0.82 | HTR1A (0.58) | HTR1AADRB1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL30839785 | 0.82 | HTR1A (0.58) | HTR1AADRB1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL24632769 | 0.81 | ADRB1 (0.55) | HTR1AADRB1HTR7HTR3AHTR3E | |
| Hydrochloric Acid SCHEMBL7241183 | 0.81 | HTR1A (0.57) | HTR1AADRB1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL31342302 | 0.81 | HTR6 (0.57) | HTR1AADRB1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL31342436 | 0.81 | ADRB1 (0.56) | HTR1AADRB1ALDH1A1LMNAHTR7 | |
| Hydrochloric Acid SCHEMBL35211564 | 0.79 | ADRB1 (0.55) | HTR1AADRB1ALDH1A1LMNAHTR7 | |
| SCHEMBL21359080 | 0.79 | HTR3A (0.49) | HTR1AADRB1SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118307496-A | Butanediamide antitumor compound and preparation method and application thereof | 江苏海洋大学 | 2024-07-09 | — | — | CN | claimed |
| WO-1999019297-A9 | SYNTHESIS OF AZETIDINE DERIVATIVES | COELACANTH CHEMICAL CORP (US) | 1999-07-08 | — | — | WO | claimed |
| WO-1999019297-A1 | SYNTHESIS OF AZETIDINE DERIVATIVES | COELACANTH CHEMICAL CORPORATION (US) | 1999-04-22 | — | — | WO | claimed |
| US-20250214977-A1 | STAT6 INHIBITORS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2025-07-03 | — | — | US | disclosed |
| CN-118307496-A | Butanediamide antitumor compound and preparation method and application thereof | 江苏海洋大学 | 2024-07-09 | — | — | CN | disclosed |
| CN-112608275-A | Application of 2, 8-bis (trifluoromethyl) -4-hydroxyquinoline derivative in preparation and prevention and treatment of agricultural diseases | 兰州大学 | 2021-04-06 | — | — | CN | disclosed |
| US-RE44205-E1 | Adenosine A2a receptor antagonists | MERCK SHARP & DOHME CORP. (US) | 2013-05-07 | — | — | US | disclosed |
| US-RE44205-E1 | Adenosine A2a receptor antagonists | MERCK SHARP & DOHME CORP. (US) | 2013-05-07 | — | — | US | disclosed |
| WO-2000063168-A1 | SYNTHESIS OF AZETIDINE DERIVATIVES | COELACANTH CHEMICAL CORPORATION (US) | 2000-10-26 | — | — | WO | disclosed |
| WO-1999019297-A9 | SYNTHESIS OF AZETIDINE DERIVATIVES | COELACANTH CHEMICAL CORP (US) | 1999-07-08 | — | — | WO | disclosed |
| WO-1999019297-A1 | SYNTHESIS OF AZETIDINE DERIVATIVES | COELACANTH CHEMICAL CORPORATION (US) | 1999-04-22 | — | — | WO | disclosed |
| US-4456756-A | PSYCHOTHERAPEUTICS | MEAD JOHNSON & COMPANY (US) | 1984-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250214977-A1 | STAT6 INHIBITORS AND USES THEREOF | STAT6, STAT5B, STAT5A | HTR1A 4232/4885ADRB1 2760/4885SLC6A2 4863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.