Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 8/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 5/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8976461 | 0.90 | ADRA1D (0.42) | HTR1AADRA1DADRA1AADRA1BMAPT | |
| SCHEMBL567883 | 0.80 | HTR1A (0.41) | HTR1AADRA1DADRA1AADRA1BMAPT | |
| SCHEMBL7464563 | 0.80 | ADRA1D (0.58) | HTR1AADRA1DADRA1AADRA1BHPGD | |
| SCHEMBL7464571 | 0.80 | ADRA1D (0.58) | HTR1AADRA1DADRA1AADRA1BHPGD | |
| SCHEMBL6628867 | 0.79 | DRD2 (0.34) | HTR1ATDP1L3MBTL1POLBHPGD | |
| SCHEMBL6628639 | 0.79 | DRD2 (0.34) | HTR1ATDP1L3MBTL1POLBHPGD | |
| SCHEMBL14364261 | 0.75 | ADRA2A (0.52) | HTR1AADRA1DADRA1AADRA1BHPGD | |
| SCHEMBL11879674 | 0.75 | KDM1A (0.41) | HTR1AMAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL10522223 | 0.75 | MAOB (0.53) | HTR1AMAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL21198165 | 0.74 | MAOB (0.60) | HPGDFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000058301-A1 | N-[2-(4-AMINOPHYL)ETHYL]-2,3-DIHYDRO-1,4-BENZODIOXINE-2-METHANAMINE, PRODUCTION AND THERAPEUTIC USE THEREOF | SANOFI-SYNTHELABO (FR) | 2000-10-05 | — | — | WO | disclosed |
| US-5480905-A | ANTIDEPRESSANTS, ANXIOLYTIC AGENTS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1996-01-02 | — | — | US | disclosed |
| EP-0565732-A1 | BENZODIOXANE DERIVATIVE | Chugai Seiyaku Kabushiki Kaisha (JP) | 1993-10-20 | — | — | EP | disclosed |