Biphenyl

Biphenyl

SCHEMBL819251

C1=CC([Ti]C2C=Cc3ccccc32)c2ccccc21.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.36

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Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
HTR2A P28223 1/20 0.35
HTR6 P50406 1/20 0.35
SIGMAR1 Q99720 6/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1820089 0.92 HTR2A (0.40) HTR2AHTR6SIGMAR1
Fluoromethane SCHEMBL8528917 0.86 HTR2A (0.36) HTR2AHTR6SIGMAR1
SCHEMBL6535429 0.83 SIGMAR1 (0.39) ALDH1A1HTR2AHTR6SIGMAR1
SCHEMBL8779530 0.81 HTR2A (0.33) HTR2AHTR6SIGMAR1
SCHEMBL8779476 0.80 HTR6 (0.31) HTR2AHTR6
SCHEMBL9075904 0.79 HTR2A (0.38) HTR2AHTR6SIGMAR1
SCHEMBL8779569 0.75 HTR2A (0.33) HTR2AHTR6SIGMAR1
SCHEMBL7764724 0.75 HTR6 (0.41) HTR2AHTR6SIGMAR1
Biphenyl SCHEMBL10455231 0.73 ALDH1A1 (0.38) ALDH1A1HTR2AHTR6SIGMAR1
Biphenyl SCHEMBL9278337 0.72 ALDH1A1 (0.36) ALDH1A1HTR2AHTR6SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 320 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6982236-B2 Process to polymerize olefins UNIVATION TECHNOLOGIES, LLC (US) 2006-01-03 US claimed
US-6897273-B2 Catalyst composition, method of polymerization and polymer therefrom UNIVATION TECHNOLOGIES, LLC (US) 2005-05-24 US claimed
EP-1392743-A2 CATALYST COMPOSITION, METHOD OF POLYMERIZATION AND POLYMER THEREFROM Univation Technologies LLC (US) 2004-03-03 EP claimed
US-20040039138-A1 Catalyst preparation method WENZEL TIMOTHY T (US) 2004-02-26 US claimed
US-6656866-B2 Metallocene and non-metallocene, homogeneous catalysts, particularly for use in the economical gas and slurry phase processes; spray dried olefin polymerization catalysts UNIVATION TECHNOLOGIES, LLC 2003-12-02 US claimed
US-20030207762-A9 CATALYST PREPARATION METHOD UNIVATION TECHNOLOGIES, LLC 2003-11-06 US claimed
EP-1358216-A2 START-UP PROCEDURE FOR MULTIPLE CATALYST POLYMERIZATION SYSTEMS Univation Technologies LLC (US) 2003-11-05 EP claimed
US-6620894-B2 Calibration; using coordination catalyst UNIVATION TECHNOLOGIES, LLC 2003-09-16 US claimed
US-20020132937-A1 Start-up procedure for multiple catalyst polymerization systems UNIVATION TECHNOLOGIES, LLC 2002-09-19 US claimed
US-20020119890-A1 Catalyst preparation method WENZEL TIMOTHY T (US) 2002-08-29 US claimed
US-20020103310-A1 Catalyst composition, method of polymerization and polymer therefrom UNIVATION TECHNOLOGIES, LLC 2002-08-01 US claimed
WO-2002050127-A2 START-UP PROCEDURE FOR MULTIPLE CATALYST POLYMERIZATION SYSTEMS UNIVATION TECHNOLOGIES, LLC (US) 2002-06-27 WO claimed
WO-2002046250-A2 CATALYST COMPOSITION, METHOD OF POLYMERIZATION AND POLYMER THEREFROM UNIVATION TECHNOLOGIES, LLC (US) 2002-06-13 WO claimed
EP-4384556-A1 PROCESS FOR PRODUCING POLYOLEFIN GRANULAR RESIN WITH INCREASED SETTLED BULK DENSITY W. R. Grace & Co.-Conn (US) 2024-06-19 EP disclosed
WO-2023177433-A1 PROCESS FOR PRODUCING HEAT TREATED SUPPORTED ALUMINOXANES IN AN ALIPHATIC SOLVENT USING SOLID ALUMINOXANES W.R. GRACE & CO.-CONN. (US) 2023-09-21 WO disclosed
WO-2023178116-A1 SILICA-SUPPORTED POLYOLEFIN CATALYST SYSTEM W. R. GRACE & CO.-CONN (US) 2023-09-21 WO disclosed
EP-0226463-A1 Polymerization catalyst EXXON CHEMICAL PATENTS INC. (US) 1987-06-24 EP disclosed
WO-1987003604-A1 NEW POLYMERIZATION CATALYST EXXON CHEMICAL PATENTS, INC. (US) 1987-06-18 WO disclosed
WO-1987002991-A1 SUPPORTED POLYMERIZATION CATALYST EXXON CHEMICAL PATENTS, INC. (US) 1987-05-21 WO disclosed
EP-0206794-A1 Supported polymerization catalyst EXXON CHEMICAL PATENTS INC. (US) 1986-12-30 EP disclosed