SCHEMBL8779476

SCHEMBL8779476

C1=CC([Ti]C2C=Cc3ccccc32)c2ccccc21.Cl[Si](Cl)(c1ccccc1)c1ccccc1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.31
HTR2A P28223 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8779530 0.84 HTR2A (0.33) HTR6HTR2A
SCHEMBL1820089 0.84 HTR2A (0.40) HTR6HTR2A
Biphenyl SCHEMBL819251 0.80 ALDH1A1 (0.36) HTR6HTR2A
SCHEMBL8779569 0.79 HTR2A (0.33) HTR6HTR2A
Fluoromethane SCHEMBL8528917 0.78 HTR2A (0.36) HTR6HTR2A
SCHEMBL8779526 0.77 HTR6 (0.31) HTR6HTR2A
SCHEMBL8779509 0.77 HTR6 (0.31) HTR6HTR2A
SCHEMBL9075904 0.76 HTR2A (0.38) HTR6HTR2A
SCHEMBL6535429 0.76 SIGMAR1 (0.39) HTR6HTR2A
SCHEMBL8369966 0.70 HTR6 (0.33) HTR6HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0730003-B1 Polypropylene resin composition and molded product TOSOH CORP (JP) 1997-12-29 EP disclosed
US-5608008-A ETHYLENE-A-OLEFIN COPOLYMER ELASTOMER TOSOH CORPORATION (JP) 1997-03-04 US disclosed
EP-0730003-A1 Polypropylene resin composition and molded product Tosoh Corporation (JP) 1996-09-04 EP disclosed