Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | TACR3 | P29371 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TOP2A | P11388 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7669102 | 0.74 | CRHBP (0.43) | NPC1RAB9ASYKCRHBPCRHR2 | |
| SCHEMBL7660400 | 0.70 | RAB9A (0.52) | NPC1RAB9ANAMPTSMN1; SMN2KMT2A | |
| SCHEMBL8184184 | 0.70 | RAB9A (0.52) | NPC1RAB9ANAMPTSMN1; SMN2KMT2A | |
| SCHEMBL7661047 | 0.69 | RAB9A (0.54) | NPC1RAB9ACRHBPCRHR2NAMPT | |
| SCHEMBL7043026 | 0.69 | POLB (0.62) | NPC1RAB9ASYKSMN1; SMN2KMT2A | |
| SCHEMBL7661054 | 0.69 | RAB9A (0.53) | NPC1RAB9ANAMPTSMN1; SMN2KMT2A | |
| SCHEMBL12872990 | 0.68 | ALDH1A1 (0.56) | NPC1RAB9ASYKSMN1; SMN2KMT2A | |
| SCHEMBL31455060 | 0.68 | NPC1 (0.55) | NPC1RAB9ASYKSMN1; SMN2KMT2A | |
| SCHEMBL28493853 | 0.68 | KDM4E (0.60) | SMN1; SMN2KMT2AKDM4EHSD17B10 | |
| SCHEMBL7400180 | 0.68 | MGLL (0.50) | NPC1RAB9ASYKSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0968186-A1 | IMPROVED POLYAMIDES FOR BINDING IN THE MINOR GROOVE OF DOUBLE STRANDED DNA | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998037066-A1 | IMPROVED POLYAMIDES FOR BINDING IN THE MINOR GROOVE OF DOUBLE STRANDED DNA | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1998-08-27 | — | — | WO | disclosed |