Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CACNA1G | O43497 | 3/20 | 0.43 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.43 |
| ▸ | CACNA1I | Q9P0X4 | 3/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | CDC7 | O00311 | 1/20 | 0.42 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | PAK4 | O96013 | 1/20 | 0.42 |
| ▸ | PRKACA | P17612 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.42 |
| ▸ | CLK2 | P49760 | 1/20 | 0.42 |
| ▸ | CDK7 | P50613 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8185813 | 0.90 | CNR2 (0.48) | ALDH1A1LMNAHSP90AB1MEN1KMT2A | |
| SCHEMBL8191026 | 0.83 | ALDH1A1 (0.43) | ALDH1A1LMNACACNA1HHSP90AB1MEN1 | |
| SCHEMBL8192162 | 0.83 | TGM2 (0.40) | ALDH1A1LMNAHSP90AB1MEN1KMT2A | |
| SCHEMBL8198730 | 0.82 | HSP90AB1 (0.43) | ALDH1A1LMNAHSP90AB1MEN1KMT2A | |
| SCHEMBL8193111 | 0.81 | LMNA (0.41) | ALDH1A1LMNAHSP90AB1MEN1KMT2A | |
| SCHEMBL4737953 | 0.81 | AURKA (0.42) | ALDH1A1LMNAMEN1KMT2AUSP2 | |
| SCHEMBL8188625 | 0.80 | LMNA (0.40) | ALDH1A1LMNAHSP90AB1MEN1KMT2A | |
| SCHEMBL4735205 | 0.79 | ALDH1A1 (0.41) | ALDH1A1LMNAMEN1KMT2AUSP2 | |
| SCHEMBL8188226 | 0.76 | DNM1L (0.42) | ALDH1A1LMNAMEN1KMT2AUSP2 | |
| SCHEMBL8193350 | 0.76 | HRH4 (0.40) | ALDH1A1LMNAMEN1KMT2AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | disclosed |