Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.40 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.40 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.40 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.40 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.40 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4737523 | 0.83 | ALDH1A1 (0.45) | ALDH1A1LMNAACHEMEN1KMT2A | |
| SCHEMBL4739034 | 0.83 | ACHE (0.40) | ACHEOPRM1OPRD1OPRK1S1PR1 | |
| SCHEMBL8185813 | 0.81 | CNR2 (0.48) | ALDH1A1LMNAUSP2MEN1KMT2A | |
| SCHEMBL8193397 | 0.79 | ALDH1A1 (0.47) | ALDH1A1LMNAUSP2MEN1KMT2A | |
| SCHEMBL4733711 | 0.78 | LMNA (0.39) | ALDH1A1LMNAACHEOPRM1HPGD | |
| SCHEMBL8191026 | 0.77 | ALDH1A1 (0.43) | ALDH1A1LMNAUSP2MEN1KMT2A | |
| SCHEMBL4734946 | 0.77 | LMNA (0.58) | ALDH1A1LMNAOPRM1MEN1KMT2A | |
| SCHEMBL8198730 | 0.76 | HSP90AB1 (0.43) | ALDH1A1LMNAUSP2MEN1KMT2A | |
| SCHEMBL3821794 | 0.76 | OPRM1 (0.39) | ALDH1A1LMNAACHEOPRM1S1PR1 | |
| SCHEMBL3059109 | 0.75 | ACHE (0.39) | LMNAACHEOPRM1S1PR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |