SCHEMBL8194012

SCHEMBL8194012

[c]1ccc(N2CCC(=NOC3CCOCC3)CC2)nc1

nearest known ligand 0.43

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ADK P55263 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8185210 0.88 ADK (0.33) ADK
SCHEMBL8199233 0.82 ADK (0.42) ADK
SCHEMBL8194100 0.81 ADK (0.43) ADK
SCHEMBL8193374 0.81
SCHEMBL8192330 0.79 ADK (0.30) ADK
SCHEMBL8219366 0.76 ALDH1A1 (0.33)
SCHEMBL182759 0.74 ALDH1A1 (0.44)
SCHEMBL8192471 0.74 GPR119 (0.32)
SCHEMBL8197207 0.72 GAA (0.33)
SCHEMBL4778875 0.71 HRH3 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2000023444-A1 5,7-DISUBSTITUTED-4-AMINOPYRIDO[2,3-D]PYRIMIDINE COMPOUNDS ABBOTT LABORATORIES (US) 2000-04-27 WO claimed
WO-2000023444-A1 5,7-DISUBSTITUTED-4-AMINOPYRIDO[2,3-D]PYRIMIDINE COMPOUNDS ABBOTT LABORATORIES (US) 2000-04-27 WO disclosed