Sugi Predict

Sugi Predict / Compounds / SCHEMBL819619

SCHEMBL819619

SCHEMBL819619

O=C(O)C1=CCC(C(=O)O)CC1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 4/20 0.68
▸ LMNA P02545 3/20 0.68
▸ CES2 O00748 1/20 0.53
▸ GABRR1 P24046 4/20 0.44
▸ GABRP O00591 4/20 0.39
▸ GABRD O14764 4/20 0.39
▸ GABRA1 P14867 4/20 0.39
▸ GABRB1 P18505 4/20 0.39
▸ GABRG2 P18507 4/20 0.39
▸ GABRB3 P28472 4/20 0.39
▸ GABRA5 P31644 4/20 0.39
▸ GABRA3 P34903 4/20 0.39
▸ GABRA2 P47869 4/20 0.39
▸ GABRB2 P47870 4/20 0.39
▸ GABRA4 P48169 4/20 0.39
▸ GABRE P78334 4/20 0.39
▸ GABRA6 Q16445 4/20 0.39
▸ GABRG1 Q8N1C3 4/20 0.39
▸ GABRG3 Q99928 4/20 0.39
▸ GABRQ Q9UN88 4/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12491776 0.88 TSHR (0.54) TSHRLMNACES2GABRR1GABRP
SCHEMBL12491771 0.86 TSHR (0.53) TSHRLMNACES2GABRR1GABRP
SCHEMBL12491773 0.86 TSHR (0.53) TSHRLMNACES2GABRR1GABRP
SCHEMBL28612818 0.85 TSHR (0.51) TSHRLMNACES2GABRR1GABRP
SCHEMBL28630710 0.85 TSHR (0.51) TSHRLMNACES2GABRR1GABRP
SCHEMBL16892249 0.84 LMNA (0.59) TSHRLMNACES2GABRR1GABRP
SCHEMBL12491109 0.82 TSHR (0.51) TSHRLMNACES2GABRR1GABRP
SCHEMBL27633891 0.81 LMNA (0.47) TSHRLMNACES2GABRR1GABRP
Perillic Acid SCHEMBL8434974 0.81 TSHR (1.00) TSHRLMNACES2GABRR1TRPA1
Perillic Acid SCHEMBL19341660 0.81 TSHR (1.00) TSHRLMNACES2GABRR1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 669 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9957218-B2 Isomerization of muconic acid IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2018-05-01 — — US claimed
US-20170129839-A1 ISOMERIZATION OF MUCONIC ACID IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2017-05-11 — — US claimed
US-7820314-B2 Proton-conducting membrane and use thereof BASF FUEL CELL RESEARCH GMBH (DE) 2010-10-26 — — US claimed
EP-1031615-B1 Aqueous process for the preparation of linear quinacridones having a reduced particle size CIBA SC HOLDING AG (CH) 2003-07-23 — — EP claimed
EP-1031615-A2 Aqueous process for the preparation of linear quinacridones having a reduced particle size Ciba SC Holding AG (CH) 2000-08-30 — — EP claimed
US-5928460-A APPLYING IN LIQUID FORM TO A SURFACE OF A SUBSTRATE A WATER DISPERSIBLE ADHESIVE COMPOSITION COMPRISING A COPOLYESTER, A TACKIFIER, AN EXTENDING OIL, AN ANTIOXIDANT STABILIZER; APPLYING A SECOND SURFACE OF A SUBSTRATE TO FORM LAMINATE EASTMAN CHEMICAL COMPANY (US) 1999-07-27 — — US claimed
EP-0638102-A1 THERMALLY STABLE POLYESTERS CONTAINING TRANS-4,4'-STILBENEDICARBOXYLIC ACID. EASTMAN CHEM CO (US) 1995-02-15 — — EP claimed
WO-1994014871-A1 POLYESTER COATINGS CONTAINING COVALENTLY-BOUND MESOGENIC MONOMERS EASTMAN KODAK COMPANY (US) 1994-07-07 — — WO claimed
WO-1993022363-A1 THERMALLY STABLE POLYESTERS CONTAINING TRANS-4,4'-STILBENEDICARBOXYLIC ACID EASTMAN CHEMICAL COMPANY (US) 1993-11-11 — — WO claimed
US-5256761-A Polyester coatings containing covalently-bound mesogenic monomers EASTMAN KODAK COMPANY (US) 1993-10-26 — — US claimed
EP-0242959-B1 OPTICALLY ANISOTROPIC MELT FORMING AROMATIC COPOLYESTERS BASED ON T-BUTYLHYDROQUINONE E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-10-03 — — EP claimed
EP-0242959-A2 Optically anisotropic melt forming aromatic copolyesters based on t-butylhydroquinone E.I. DU PONT DE NEMOURS AND COMPANY (US) 1987-10-28 — — EP claimed
US-4664972-A MOLDINGS, FIBERS, FILMS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-05-12 — — US claimed
EP-4724195-A2 METAL-ORGANIC FRAMEWORK (MOF) COMPOSITIONS, PROCESS OF MAKING AND PROCESS OF USE THEREOF Numat Technologies Inc. (US) 2026-04-15 — — EP disclosed
EP-4703440-A1 INK COMPOSITION FOR METAL PRINTING Sakata INX Corporation (JP) 2026-03-04 — — EP disclosed
US-12552888-B2 Curable resin composition and display device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2026-02-17 — — US disclosed
US-3969294-A Segmented copolyester adhesives stabilized by alkaline earth oxides and carboxylic compounds E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-07-13 — — US disclosed
US-3966656-A FIBER AND FILM FORMING E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-06-29 — — US disclosed
US-3966841-A POLYESTER OF TEREPHTHALIC ACID AND ETHYLENE GLYCOL OR 1,4-BUTANEDIOL OR 1,4-CYCLOHEXANEDIMETHANOL EASTMAN KODAK COMPANY (US) 1976-06-29 — — US disclosed
US-3943189-A Process for preparation of copolymers from polyesters and aliphatic polyformals EASTMAN KODAK COMPANY (US) 1976-03-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12552888-B2 Curable resin composition and display device RAD51, LPO, FTO TSHR 3729/4885LMNA 2961/4885CES2 2246/4885
US-20170129839-A1 ISOMERIZATION OF MUCONIC ACID MUC1, CA6, CA13 TSHR 4093/4885LMNA 1600/4885CES2 1504/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.