Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 6/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | SIK1 | P57059 | 2/20 | 0.34 |
| ▸ | SIK2 | Q9H0K1 | 2/20 | 0.34 |
| ▸ | SIK3 | Q9Y2K2 | 2/20 | 0.34 |
| ▸ | GAK | O14976 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | EPHA1 | P21709 | 1/20 | 0.34 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.34 |
| ▸ | EPHA3 | P29320 | 1/20 | 0.34 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8522266 | 0.88 | ADORA2B (0.51) | ADORA2BMAPTPDE4APDE4BPDE4C | |
| SCHEMBL6272293 | 0.86 | ADORA2B (0.53) | ADORA2BMAPTPDE4APDE4BPDE4C | |
| SCHEMBL8536000 | 0.86 | ADORA2B (0.53) | ADORA2BMAPTPDE4APDE4BPDE4C | |
| SCHEMBL4384737 | 0.86 | ADORA2B (0.53) | ADORA2BMAPTPDE4APDE4BPDE4C | |
| SCHEMBL6272726 | 0.86 | PDE4A (0.49) | ADORA2BMAPTPDE4APDE4BPDE4C | |
| Hydrochloric Acid SCHEMBL258895 | 0.85 | ADORA2B (0.52) | ADORA2BMAPTPDE4APDE4BPDE4C | |
| SCHEMBL3671337 | 0.83 | PNP (0.37) | ADORA2BMAPTLMNACYP1A2PDE4A | |
| SCHEMBL667794 | 0.83 | PDE4A (0.49) | ADORA2BPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9960806 | 0.82 | PNP (0.38) | ADORA2BMAPTLMNACYP1A2PDE4A | |
| Acetic Acid SCHEMBL4280715 | 0.81 | ADORA2B (0.48) | ADORA2BMAPTPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912751-B1 | PROCESS FOR PREPARATION OF D-PROLINE DERIVATIVES BY MEANS OF MICRO-ORGANISMS | LONZA AG (CH) | 2000-10-04 | — | — | EP | disclosed |
| EP-0912751-A1 | PROCESS FOR PREPARATION OF D-PROLINE DERIVATIVES BY MEANS OF MICRO-ORGANISMS | LONZA AG (CH) | 1999-05-06 | — | — | EP | disclosed |
| WO-1998001577-A1 | PROCESS FOR PREPARATION OF D-PROLINE DERIVATIVES BY MEANS OF MICRO-ORGANISMS | LONZA AG (CH) | 1998-01-15 | — | — | WO | disclosed |