Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.31 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MITF | O75030 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8206453 | 0.86 | EPHX2 (0.37) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL4754404 | 0.72 | LMNA (0.37) | ALDH1A1LMNATDP1THRB | |
| SCHEMBL3831293 | 0.64 | TDP1 (0.36) | LMNATDP1 | |
| SCHEMBL9637089 | 0.62 | TTR (0.42) | ALDH1A1LMNASMN1; SMN2KDM4EMAPK1 | |
| SCHEMBL17137947 | 0.59 | ALDH1A1 (0.62) | ALDH1A1LMNASMN1; SMN2HTTNCOA1 | |
| SCHEMBL17137945 | 0.59 | ALDH1A1 (0.62) | ALDH1A1LMNASMN1; SMN2HTTNCOA1 | |
| SCHEMBL11739515 | 0.59 | NOD1 (0.49) | ALDH1A1LMNASMN1; SMN2TDP1 | |
| SCHEMBL11739510 | 0.59 | NOD1 (0.49) | ALDH1A1LMNASMN1; SMN2TDP1 | |
| SCHEMBL941953 | 0.59 | LMNA (0.47) | ALDH1A1LMNASMN1; SMN2HTTTDP1 | |
| SCHEMBL2377759 | 0.58 | ALDH1A1 (0.59) | ALDH1A1LMNASMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0703790-B1 | IODINATED PARAMAGNETIC CHELATES, AND THEIR USE AS CONTRAST AGENTS | BRACCO SPA (IT) | 2000-08-16 | — | — | EP | disclosed |
| US-5660814-A | Iodinated paramagnetic chelates, and their use as contrast agents | DIBRA S.P.A. (IT) | 1997-08-26 | — | — | US | disclosed |