Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 10/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 9/20 | 0.34 |
| ▸ | CXCR1 | P25024 | 4/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | SLC22A6 | Q4U2R8 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.34 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9696073 | 0.75 | LMNA (0.49) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| SCHEMBL3179347 | 0.72 | AKR1C3 (0.36) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| SCHEMBL18242674 | 0.72 | TTR (0.43) | TTRGABRA1GABRB1GABRB2 | |
| SCHEMBL28713389 | 0.71 | TTR (0.48) | TTRGABRA1GABRB1GABRB2 | |
| SCHEMBL21582163 | 0.70 | LCK (0.40) | PTGS2PTGS1SLC22A6ALDH1A1HPGD | |
| SCHEMBL1741372 | 0.70 | PTGS2 (0.44) | TTRPTGS2PTGS1CXCR1CXCR2 | |
| SCHEMBL4754404 | 0.69 | LMNA (0.37) | TTRPTGS2LMNAMAPTALDH1A1 | |
| SCHEMBL462541 | 0.67 | PTGS2 (0.61) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| SCHEMBL6399236 | 0.67 | PTGS2 (0.41) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| SCHEMBL7146446 | 0.67 | PTGS2 (0.41) | PTGS2PTGS1CXCR1CXCR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5160725-A | Contrast agent for diagnostic imaging, polyethylene glycol phosphates and carboxylates as stabilizers | SILICA GEL GESELLSCHAFT MBH ADSORPTIONS-TECHNIK, APPARATEBAU (DE) | 1992-11-03 | — | — | US | claimed |
| EP-0284549-B1 | MAGNETIC FLUID COMPOSITIONS | Silica Gel Ges.mbH Absorptionstechnik, Apparatebau (DE) | 1992-07-15 | — | — | EP | claimed |
| US-5160725-A | Contrast agent for diagnostic imaging, polyethylene glycol phosphates and carboxylates as stabilizers | SILICA GEL GESELLSCHAFT MBH ADSORPTIONS-TECHNIK, APPARATEBAU (DE) | 1992-11-03 | — | — | US | disclosed |