Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8336119 | 0.87 | TTR (0.33) | LMNATBXA2RCYP1A2CYP2C9CHRM1 | |
| SCHEMBL8199024 | 0.72 | ALDH1A1 (0.37) | LMNATDP1THRBALDH1A1 | |
| SCHEMBL3831293 | 0.71 | TDP1 (0.36) | LMNATBXA2RCYP1A2CYP2C9CHRM1 | |
| SCHEMBL6778049 | 0.69 | FABP3 (0.43) | RXRASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL9637089 | 0.69 | TTR (0.42) | LMNACYP1A2CYP2C9HIF1ATTR | |
| SCHEMBL9696079 | 0.68 | TTR (0.33) | LMNATBXA2RCYP1A2CYP2C9CHRM1 | |
| SCHEMBL7426518 | 0.68 | DPP4 (0.48) | LMNAMEN1KMT2ASLC1A3SLC1A2 | |
| SCHEMBL2298439 | 0.68 | DPP4 (0.48) | LMNAMEN1KMT2ASLC1A3SLC1A2 | |
| SCHEMBL7356667 | 0.68 | SLC1A1 (0.39) | NR1I2SLC1A3SLC1A2SLC1A1DPP7 | |
| Hydrochloric Acid SCHEMBL6378952 | 0.68 | TPMT (0.39) | CYP1A2TDP1MEN1KMT2ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008144399-A1 | COMPLEXES COMPRISING α2-ADRENERGIC RECEPTOR AGONISTS AND COMPOSITIONS | BAUSCH & LOMB INCORPORATED (US) | 2008-11-27 | — | — | WO | disclosed |
| US-20080293728-A1 | Complexes Comprising alpha2-Adrenergic Receptor Agonists and Compositions | BAUSCH & LOMB INCORPORATED | 2008-11-27 | — | — | US | disclosed |
| US-6602419-B1 | Nanofiltration before oxidation | BRACCO IMAGINING S.P.A. (IT) | 2003-08-05 | — | — | US | disclosed |
| EP-1133346-B1 | A PROCESS FOR THE RECOVERY OF IODINE FROM AQUEOUS SOLUTIONS CONTAINING IODINATED ORGANIC COMPOUNDS | BRACCO IMAGING SPA (IT) | 2003-03-26 | — | — | EP | disclosed |
| EP-0703790-B1 | IODINATED PARAMAGNETIC CHELATES, AND THEIR USE AS CONTRAST AGENTS | BRACCO SPA (IT) | 2000-08-16 | — | — | EP | disclosed |
| US-5660814-A | Iodinated paramagnetic chelates, and their use as contrast agents | DIBRA S.P.A. (IT) | 1997-08-26 | — | — | US | disclosed |
| US-4925649-A | Radioiodinated diacylglycerol analogues and methods of use | THE UNIVERSITY OF MICHIGAN (US) | 1990-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293728-A1 | Complexes Comprising alpha2-Adrenergic Receptor Agonists and Compositions | ADRB2, ADRA2A, ADRA2C | LMNA 840/4885TBXA2R 40/4885CYP1A2 749/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.