Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 7/20 | 0.52 |
| ▸ | MMP3 | P08254 | 7/20 | 0.52 |
| ▸ | MMP7 | P09237 | 5/20 | 0.52 |
| ▸ | MMP2 | P08253 | 3/20 | 0.52 |
| ▸ | MMP13 | P45452 | 2/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 3/20 | 0.49 |
| ▸ | MMP8 | P22894 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | PKLR | P30613 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8206367 | 0.88 | HSD11B1 (0.57) | MMP1MMP3MMP7MMP2MMP13 | |
| SCHEMBL9208624 | 0.88 | PKM (0.46) | MMP2HTTPKMALDH1A1POLB | |
| SCHEMBL10905546 | 0.76 | ALDH1A1 (0.41) | HTTPKMRAB9ANPC1ALDH1A1 | |
| SCHEMBL12455819 | 0.74 | NPC1 (0.63) | HSD11B1HTTPKMRAB9ANPC1 | |
| SCHEMBL9213545 | 0.73 | CYP2C19 (0.53) | HTTPKMRAB9ANPC1ALDH1A1 | |
| SCHEMBL8527273 | 0.72 | MMP9 (0.50) | MMP1MMP3MMP7MMP2MMP13 | |
| SCHEMBL8498354 | 0.72 | MMP9 (0.50) | MMP1MMP3MMP7MMP2MMP13 | |
| SCHEMBL21540491 | 0.71 | HSD11B1 (0.48) | MMP1MMP3MMP7MMP2MMP13 | |
| SCHEMBL20153278 | 0.70 | NPC1 (0.54) | MMP1MMP2MMP13HSD11B1MMP9 | |
| SCHEMBL11888962 | 0.69 | PKM (0.65) | HSD11B1HTTPKMRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6121272-A | Bidentate metalloprotease inhibitors | THE PROCTER & GAMBLE COMPANY (US) | 2000-09-19 | — | — | US | disclosed |