Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.36 |
| ▸ | GRK6 | P43250 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8195495 | 0.84 | TP53 (0.37) | HTTSMN1; SMN2ALDH1A1NPSR1MAPT | |
| SCHEMBL8195834 | 0.84 | IKBKE (0.39) | GRK6SMN1; SMN2ALDH1A1DYRK1AMAPT | |
| SCHEMBL8200074 | 0.83 | LMNA (0.38) | HTTSMN1; SMN2MAPK10MAPTPOLB | |
| SCHEMBL8195725 | 0.83 | RPS6KA3 (0.40) | GRK6HTTSMN1; SMN2MAPK10ALDH1A1 | |
| SCHEMBL8196103 | 0.83 | GRK6 (0.38) | GRK6SMN1; SMN2ALDH1A1MAPTMEN1 | |
| SCHEMBL8197299 | 0.82 | MAPK14 (0.38) | HTTSMN1; SMN2MAPK10ALDH1A1MAPT | |
| SCHEMBL8196169 | 0.81 | ALDH1A1 (0.37) | KMOSMN1; SMN2RIPK2ALDH1A1MAPT | |
| SCHEMBL8188126 | 0.73 | MEN1 (0.40) | HTTSMN1; SMN2ALDH1A1MEN1GAA | |
| SCHEMBL8196014 | 0.72 | ALDH1A1 (0.37) | KMOSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL8196005 | 0.72 | MEN1 (0.39) | HTTSMN1; SMN2ALDH1A1MEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000018741-A2 | PYRAZOLE COMPOUNDS AS COX-2 INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-06 | — | — | WO | disclosed |