Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | CNR2 | P34972 | 2/20 | 0.48 |
| ▸ | KDR | P35968 | 9/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.47 |
| ▸ | TNNI3K | Q59H18 | 6/20 | 0.47 |
| ▸ | BRAF | P15056 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | KIT | P10721 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7780181 | 0.88 | KDR (0.45) | MAPTGAACNR2KDRMAPK14 | |
| SCHEMBL4244096 | 0.81 | L3MBTL1 (0.57) | MAPTGAAKDRL3MBTL1MAPK1 | |
| SCHEMBL7783065 | 0.78 | ALDH1A1 (0.54) | MAPTGAAKDRL3MBTL1ALDH1A1 | |
| SCHEMBL8773803 | 0.77 | ALDH1A1 (0.53) | MAPTGAAKDRL3MBTL1ALDH1A1 | |
| SCHEMBL7780979 | 0.76 | ALDH1A1 (0.52) | MAPTGAAKDRL3MBTL1MAPK1 | |
| SCHEMBL12825474 | 0.75 | KDR (0.62) | MAPTGAAKDRL3MBTL1MAPK1 | |
| SCHEMBL16202045 | 0.75 | KDR (0.62) | MAPTKDRL3MBTL1MAPK1ALDH1A1 | |
| SCHEMBL8185361 | 0.75 | KDR (0.46) | KDRBRAFFLT1 | |
| SCHEMBL4239378 | 0.74 | ABL1 (0.69) | MAPTGAAKDRMAPK1MAPK14 | |
| SCHEMBL7775883 | 0.73 | MAPT (0.48) | MAPTGAAKDRL3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000049001-A2 | PHENOXY-, PHENYLTHIO-, PHENYLAMINO-, BENZYLOXY-, BENZYLTHIO- OR BENZYLAMINOPYRIMIDINE INSECTIDICES AND ACARICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-08-24 | — | — | WO | disclosed |