Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 10/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 9/20 | 0.44 |
| ▸ | TNNI3K | Q59H18 | 9/20 | 0.44 |
| ▸ | BRAF | P15056 | 8/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | RAF1 | P04049 | 1/20 | 0.41 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7776085 | 0.87 | KDR (0.43) | MAPTKDRMAPK14TNNI3KBRAF | |
| SCHEMBL4244096 | 0.84 | L3MBTL1 (0.57) | MAPTALDH1A1POLBL3MBTL1KDR | |
| SCHEMBL16202045 | 0.81 | KDR (0.62) | MAPTALDH1A1POLBL3MBTL1KDR | |
| SCHEMBL12825474 | 0.81 | KDR (0.62) | MAPTALDH1A1POLBL3MBTL1KDR | |
| SCHEMBL7780979 | 0.79 | ALDH1A1 (0.52) | MAPTALDH1A1POLBL3MBTL1KDR | |
| SCHEMBL7783065 | 0.78 | ALDH1A1 (0.54) | MAPTALDH1A1POLBL3MBTL1KDR | |
| SCHEMBL8773803 | 0.77 | ALDH1A1 (0.53) | MAPTALDH1A1POLBL3MBTL1KDR | |
| Hydrochloric Acid SCHEMBL7776436 | 0.76 | MAPT (0.48) | MAPTALDH1A1POLBL3MBTL1KDR | |
| SCHEMBL7780158 | 0.76 | THRB (0.40) | ALDH1A1POLBMAPK1 | |
| SCHEMBL8773158 | 0.75 | MAPT (0.65) | MAPTALDH1A1POLBL3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972770-B1 | Acaricidal and insecticidal substituted pyrimidines and a process for the preparation thereof | BASF AG (DE) | 2001-09-19 | — | — | EP | claimed |
| US-6281219-B1 | 4,6-BIS-ARYL-PYRIMIDINES WHEREIN THE AROMATIC GROUPS ARE ATTACHED VIA TWO LINKING GROUPS WHICH ARE DIFFERENT FROM ONE ANOTHER. | AMERICAN CYANAMID CO. | 2001-08-28 | — | — | US | claimed |
| EP-0972770-A1 | Acaricidal and insecticidal substituted pyrimidines and a process for the preparation thereof | American Cyanamid Company (US) | 2000-01-19 | — | — | EP | claimed |
| EP-0972770-B1 | Acaricidal and insecticidal substituted pyrimidines and a process for the preparation thereof | BASF AG (DE) | 2001-09-19 | — | — | EP | disclosed |
| EP-0972770-A1 | Acaricidal and insecticidal substituted pyrimidines and a process for the preparation thereof | American Cyanamid Company (US) | 2000-01-19 | — | — | EP | disclosed |