Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.67 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | KIF11 | P52732 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | PDK1 | Q15118 | 6/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 6/20 | 0.47 |
| ▸ | PDK3 | Q15120 | 6/20 | 0.47 |
| ▸ | PDK4 | Q16654 | 6/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4281969 | 0.92 | MAPT (0.57) | L3MBTL1CA12CA1CA2CA7 | |
| SCHEMBL17368411 | 0.92 | KIF11 (0.58) | L3MBTL1CA12CA1CA2CA7 | |
| SCHEMBL28307531 | 0.90 | ALDH1A1 (0.57) | L3MBTL1CA12CA1CA2CA7 | |
| SCHEMBL14466017 | 0.90 | KIF11 (0.66) | L3MBTL1CA1CA2MAPTKIF11 | |
| SCHEMBL19853109 | 0.90 | PDK1 (0.62) | L3MBTL1CA12CA1CA2CA9 | |
| SCHEMBL2745516 | 0.89 | PDK1 (0.59) | L3MBTL1MAPTALDH1A1LMNARAB9A | |
| SCHEMBL15962158 | 0.88 | EPHX2 (0.57) | L3MBTL1CA12CA1CA2CA9 | |
| Hydrochloric Acid SCHEMBL19841199 | 0.88 | PDK1 (0.60) | L3MBTL1CA12CA1CA2CA9 | |
| SCHEMBL2746235 | 0.88 | L3MBTL1 (0.54) | L3MBTL1CA12CA1CA2CA7 | |
| SCHEMBL4573229 | 0.87 | L3MBTL1 (0.52) | L3MBTL1CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000071542-A1 | IMPROVED SYNTHESIS OF A TETRAAMIDO MACROCYCLE LIGAND | THE CLOROX COMPANY (US) | 2000-11-30 | — | — | WO | claimed |