Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASE1 | P07998 | 1/20 | 0.38 |
| ▸ | TK1 | P04183 | 10/20 | 0.36 |
| ▸ | TOP2A | P11388 | 1/20 | 0.36 |
| ▸ | TK2 | O00142 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9755145 | 0.98 | RNASE1 (0.38) | RNASE1TK1TOP2ATK2 | |
| SCHEMBL1705935 | 0.96 | RNASE1 (0.35) | RNASE1TK1TOP2ATK2 | |
| Succinic Acid SCHEMBL1705784 | 0.96 | RNASE1 (0.37) | RNASE1TK1TOP2ATK2 | |
| SCHEMBL8920654 | 0.94 | RNASE1 (0.36) | RNASE1TK1TOP2ATK2 | |
| SCHEMBL7640415 | 0.91 | RNASE1 (0.38) | RNASE1TK1TK2 | |
| SCHEMBL20636773 | 0.91 | LMNA (0.38) | RNASE1TOP2A | |
| SCHEMBL3612838 | 0.91 | TK1 (0.38) | RNASE1TK1 | |
| SCHEMBL1727535 | 0.90 | RNASE1 (0.40) | RNASE1TK1TK2 | |
| SCHEMBL8370048 | 0.89 | RNASE1 (0.38) | RNASE1TK1TK2 | |
| SCHEMBL7863893 | 0.87 | RNASE1 (0.37) | RNASE1TK1TOP2ATK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62201895-A | — | — | None | — | — | JP | disclosed |
| EP-4146280-A1 | LINKER COMPOUNDS | Mpeg LA, L.l.c. (US) | 2023-03-15 | — | — | EP | disclosed |
| US-8825411-B2 | Design, synthesis and assembly of synthetic nucleic acids | DNA TWOPOINTO, INC. (US) | 2014-09-02 | — | — | US | disclosed |
| EP-2441769-B1 | Design, synthesis and assembly of synthetic nucleic acids | REPLIGEN CORP (US) | 2014-05-07 | — | — | EP | disclosed |
| US-20130196864-A1 | DESIGN, SYNTHESIS AND ASSEMBLY OF SYNTHETIC NUCLEIC ACIDS | DNA TWOPOINTO, INC. (US) | 2013-08-01 | — | — | US | disclosed |
| EP-2441769-A1 | Design, synthesis and assembly of synthetic nucleic acids | REPLIGEN CORPORATION (US) | 2012-04-18 | — | — | EP | disclosed |
| EP-2205741-A2 | INCREASING ERYTHROPOIETIN USING NUCLEIC ACIDS HYBRIDIZABLE TO MICRO-RNA AND PRECURSORS THEREOF | Amgen Inc. (US) | 2010-07-14 | — | — | EP | disclosed |
| US-20090317873-A1 | Design, synthesis and assembly of synthetic nucleic acids | DNA TWOPOINTO, INC. | 2009-12-24 | — | — | US | disclosed |
| WO-2009045469-A2 | INCREASING ERYTHROPOIETIN USING NUCLEIC ACIDS HYBRIDIZABLE TO MICRO-RNA AND PRECURSORS THEREOF | AMGEN INC. (US) | 2009-04-09 | — | — | WO | disclosed |
| EP-2013345-A2 | COMPOSITIONS AND METHODS FOR MODULATION OF MCL-1 EXPRESSION | Isis Pharmaceuticals, Inc. (US) | 2009-01-14 | — | — | EP | disclosed |
| WO-1996022297-A1 | NON-NUCLEOTIDE PHOSPHORUS ESTER OLIGOMERS | PHARMAGENICS, INC. (US) | 1996-07-25 | — | — | WO | disclosed |
| US-5510476-A | SOLID PHASE SYNTHESIS USING AN ACIDIC SOLUTION OF THE SCAVENGER TO DEPROTECT THE 5'-HYDROXY AND NEUTRALIZE THE CARBO ANION RELEASED; HIGH YIELDS | ISIS PHARMACEUTICALS, INC. (US) | 1996-04-23 | — | — | US | disclosed |
| EP-0691948-A1 | PROTECTING GROUP FOR USE IN OLIGODEOXYRIBONUCLEOTIDE SYNTHESIS | Laporte PLC (GB) | 1996-01-17 | — | — | EP | disclosed |
| WO-1994022802-A1 | PROTECTING GROUP FOR USE IN OLIGODEOXYRIBONUCLEOTIDE SYNTHESIS | LAPORTE PLC (GB) | 1994-10-13 | — | — | WO | disclosed |
| WO-1994001446-A2 | DERIVATIZED ORGANIC SOLID SUPPORT FOR NUCLEIC ACID SYNTHESIS | BECKMAN INSTRUMENTS, INC. (US) | 1994-01-20 | — | — | WO | disclosed |
| US-5218102-A | Easily synthesized, hybridize well with target sequences | IMPROBIO (BE) | 1993-06-08 | — | — | US | disclosed |
| WO-1992004364-A1 | A METHOD OF LINKING NUCLEOSIDES WITH A SILOXANE BRIDGE | STERLING WINTHROP INC. (US) | 1992-03-19 | — | — | WO | disclosed |
| WO-1991004983-A1 | NUCLEOSIDE AND POLYNUCLEOTIDE THIOPHOSPHORAMIDITE AND PHOSPHORODITHIOATE COMPOUNDS AND PROCESSES | UNIVERSITY PATENTS, INC. (US) | 1991-04-18 | — | — | WO | disclosed |
| EP-0334694-A1 | Nucleic acid probes with non-radioactive labels, and preparation processes | LA REGION WALLONNE (BE) | 1989-09-27 | — | — | EP | disclosed |
| JP-S62201895-A | DEOXYNUCLEOSIDE PHOSPHORSULFIDE COMPOUND | TOAGOSEI CHEM IND CO LTD | 1987-09-05 | — | — | JP | disclosed |