Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 4/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 3/20 | 0.32 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.32 |
| ▸ | GPR18 | Q14330 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | PLK1 | P53350 | 3/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6201326 | 0.92 | L3MBTL1 (0.37) | L3MBTL1CNR2HDAC11HDAC8MMP1 | |
| SCHEMBL8193843 | 0.88 | MMP1 (0.34) | CNR2MMP1MMP9MMP13CNR1 | |
| SCHEMBL8202222 | 0.83 | CNR1 (0.38) | CNR2MMP1MMP13CNR1GPR55 | |
| SCHEMBL8893617 | 0.82 | CNR1 (0.34) | L3MBTL1CNR2MMP1MMP9MMP13 | |
| SCHEMBL6201511 | 0.79 | AR (0.35) | CNR2MMP1MMP9MMP13CNR1 | |
| SCHEMBL8200737 | 0.79 | L3MBTL1 (0.36) | L3MBTL1CNR2HDAC11HDAC8MMP1 | |
| SCHEMBL8204279 | 0.78 | ALDH1A1 (0.39) | CNR1GPR55 | |
| SCHEMBL8570819 | 0.75 | CNR1 (0.33) | L3MBTL1CNR2CNR1GPR55AR | |
| SCHEMBL6201097 | 0.74 | CNR1 (0.38) | CNR2CNR1GPR55 | |
| SCHEMBL6201198 | 0.73 | AR (0.36) | L3MBTL1CNR2MMP1MMP9MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0971744-A2 | COMBINATION THERAPY EMPLOYING ILEAL BILE ACID TRANSPORT INHIBITING BENZOTHIEPINES AND HMG Co-A REDUCTASE INHIBITORS | G.D. SEARLE & CO. (US) | 2000-01-19 | — | — | EP | disclosed |
| WO-1998040375-A2 | COMBINATION OF ILEAL BILE ACID TRANSPORT INHIBITING BENZOTHIEPINES AND HMG Co-A REDUCTASE INHIBITORS | G.D. SEARLE & CO. (US) | 1998-09-17 | — | — | WO | disclosed |