SCHEMBL8570819

SCHEMBL8570819

CCCCC(C=O)(CC)CCS(=O)(=O)c1cc(OCC)ccc1Cc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 2/20 0.33
AR P10275 1/20 0.33
ALDH1A1 P00352 2/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
PTGES O14684 1/20 0.31
ALOX5 P09917 1/20 0.31
PPARG P37231 1/20 0.31
CNR2 P34972 2/20 0.31
GPR55 Q9Y2T6 1/20 0.31
SLC5A2 P31639 1/20 0.31
S1PR1 P21453 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8893617 0.85 CNR1 (0.34) CNR1ARL3MBTL1CNR2GPR55
SCHEMBL8202222 0.83 CNR1 (0.38) CNR1ALDH1A1HPGDCNR2GPR55
SCHEMBL6202055 0.82 CNR1 (0.38) CNR1ALDH1A1CNR2GPR55
SCHEMBL8193843 0.77 MMP1 (0.34) CNR1ARCNR2GPR55
SCHEMBL6201198 0.75 AR (0.36) CNR1ARL3MBTL1CNR2GPR55
SCHEMBL8200735 0.75 L3MBTL1 (0.37) CNR1ARL3MBTL1CNR2GPR55
SCHEMBL8204279 0.75 ALDH1A1 (0.39) CNR1ALDH1A1MAPTHPGDGPR55
SCHEMBL6201097 0.74 CNR1 (0.38) CNR1ALDH1A1CNR2GPR55
SCHEMBL27534833 0.71 CNR1 (0.40) CNR1CNR2GPR55
SCHEMBL6200633 0.69 MMP2 (0.38) CNR1ALDH1A1L3MBTL1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1997033882-A9 NOVEL BENZOTHIEPINES HAVING ACTIVITY AS INHIBITORS OF ILEAL BILE ACID TRANSPORT AND TAUROCHOLATE UPTAKE 1998-02-26 WO disclosed