Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 3/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 2/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6201097 | 0.91 | CNR1 (0.38) | CNR1MTNR1AMTNR1BGPR55CNR2 | |
| SCHEMBL8893617 | 0.85 | CNR1 (0.34) | CNR1GPR55CNR2PTGDR2MMP1 | |
| SCHEMBL8193843 | 0.83 | MMP1 (0.34) | CNR1GPR55CNR2MMP1MMP13 | |
| SCHEMBL8570819 | 0.83 | CNR1 (0.33) | CNR1GPR55CNR2ALDH1A1HPGD | |
| SCHEMBL6202055 | 0.83 | CNR1 (0.38) | CNR1MTNR1AMTNR1BGPR55CNR2 | |
| SCHEMBL8200735 | 0.83 | L3MBTL1 (0.37) | CNR1GPR55CNR2MMP1MMP13 | |
| SCHEMBL8204279 | 0.83 | ALDH1A1 (0.39) | CNR1GPR55ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL8202225 | 0.78 | CNR1 (0.37) | CNR1MTNR1AMTNR1BGPR55CNR2 | |
| SCHEMBL6200633 | 0.76 | MMP2 (0.38) | CNR1CNR2ALDH1A1HPGDLTA4H | |
| SCHEMBL6201198 | 0.76 | AR (0.36) | CNR1GPR55CNR2PTGDR2MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0971744-A2 | COMBINATION THERAPY EMPLOYING ILEAL BILE ACID TRANSPORT INHIBITING BENZOTHIEPINES AND HMG Co-A REDUCTASE INHIBITORS | G.D. SEARLE & CO. (US) | 2000-01-19 | — | — | EP | disclosed |
| WO-1998040375-A2 | COMBINATION OF ILEAL BILE ACID TRANSPORT INHIBITING BENZOTHIEPINES AND HMG Co-A REDUCTASE INHIBITORS | G.D. SEARLE & CO. (US) | 1998-09-17 | — | — | WO | disclosed |