Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.40 |
| ▸ | YTHDC1 | Q96MU7 | 2/20 | 0.39 |
| ▸ | YTHDF2 | Q9Y5A9 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | LCK | P06239 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 3/20 | 0.35 |
| ▸ | GAK | O14976 | 2/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3817132 | 0.79 | PDPK1 (0.45) | ESR1PDPK1ALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL12261899 | 0.79 | YTHDC1 (0.39) | ESR1PDPK1YTHDC1YTHDF2ALDH1A1 | |
| SCHEMBL9046753 | 0.78 | PGK1 (0.41) | PDPK1YTHDC1YTHDF2ALDH1A1HSD17B10 | |
| SCHEMBL24344244 | 0.78 | ALDH1A1 (0.36) | ESR1PDPK1YTHDC1YTHDF2ALDH1A1 | |
| SCHEMBL9050477 | 0.74 | ESR1 (0.46) | ESR1ALDH1A1CYP1A2LMNACYP2D6 | |
| SCHEMBL23326914 | 0.73 | ESR1 (0.38) | ESR1PDPK1YTHDC1YTHDF2ALDH1A1 | |
| SCHEMBL14326156 | 0.71 | PDPK1 (0.39) | ESR1PDPK1ALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL11771336 | 0.70 | PDPK1 (0.38) | ESR1PDPK1ALDH1A1LCKHPGD | |
| SCHEMBL9044468 | 0.70 | ALDH1A1 (0.39) | ESR1PDPK1ALDH1A1TDP1LCK | |
| SCHEMBL6233405 | 0.70 | PDE5A (0.46) | ESR1PDPK1LCKLMNAEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008097546-A2 | COMPOUNDS THAT INHIBIT CHOLINESTERASE | COLUCID PHARMACEUTICALS, INC. (US) | 2008-08-14 | — | — | WO | disclosed |