Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.34 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.34 |
| ▸ | PLK4 | O00444 | 2/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP7 | P09237 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | PRKX | P51817 | 1/20 | 0.34 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8200073 | 0.89 | FFAR1 (0.35) | PLK4CDK2MAPTALDH1A1L3MBTL1 | |
| SCHEMBL8187580 | 0.84 | TP53 (0.37) | MEN1KMT2AALDH1A1NEK1PTGS2 | |
| SCHEMBL8202075 | 0.83 | PTGS2 (0.37) | PLK4MEN1KMT2AMAPTHTT | |
| SCHEMBL8196169 | 0.82 | ALDH1A1 (0.37) | MEN1KMT2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL8196138 | 0.82 | PTGS2 (0.36) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL8188126 | 0.82 | MEN1 (0.40) | MEN1KMT2AALDH1A1HTTPTGS2 | |
| SCHEMBL8196136 | 0.79 | PTGS2 (0.38) | DYRK1APLK4RETPRKXCDK2 | |
| SCHEMBL8196005 | 0.73 | MEN1 (0.39) | MEN1KMT2AALDH1A1HTTPTGS2 | |
| SCHEMBL8195771 | 0.73 | GRM5 (0.37) | DYRK1ADYRK1BMEN1HPGDKMT2A | |
| SCHEMBL8201297 | 0.72 | L3MBTL1 (0.37) | MEN1KMT2AMAPTALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000018741-A2 | PYRAZOLE COMPOUNDS AS COX-2 INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-06 | — | — | WO | disclosed |