Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.45 |
| ▸ | NOS1 | P29475 | 8/20 | 0.39 |
| ▸ | NOS2 | P35228 | 8/20 | 0.39 |
| ▸ | NOS3 | P29474 | 6/20 | 0.39 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.34 |
| ▸ | AOC1 | P19801 | 3/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3613070 | 0.77 | TAAR1 (0.54) | — | |
| SCHEMBL3613068 | 0.77 | TAAR1 (0.54) | — | |
| SCHEMBL15925898 | 0.71 | NOS1 (0.48) | NOS1NOS2NOS3 | |
| SCHEMBL30824586 | 0.69 | LOXL2 (0.73) | LOXL2KCNH3AOC1AOC3 | |
| SCHEMBL27140192 | 0.69 | LOXL2 (0.73) | LOXL2KCNH3AOC1AOC3 | |
| SCHEMBL19554810 | 0.69 | LOXL2 (0.41) | LOXL2KCNH3 | |
| SCHEMBL15925910 | 0.65 | NOS1 (0.54) | NOS1NOS2NOS3 | |
| SCHEMBL3878756 | 0.65 | LOXL2 (0.59) | LOXL2KCNH3AOC1AOC3 | |
| SCHEMBL10284177 | 0.65 | LOXL2 (0.59) | LOXL2KCNH3AOC1AOC3 | |
| SCHEMBL2090251 | 0.65 | LOXL2 (0.59) | LOXL2KCNH3AOC1AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008092785-A1 | NOVEL 2-AMINOOXAZOLINES AS TAAR1 LIGANDS FOR CNS DISORDERS | F. HOFFMANN-LA ROCHE AG (CH) | 2008-08-07 | — | — | WO | disclosed |