Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | TTR | P02766 | 3/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 5/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Xanthone SCHEMBL18138444 | 0.77 | MAOA (0.75) | NPC1RAB9ATTRMAOAKDM4E | |
| SCHEMBL1784133 | 0.76 | MAOA (0.62) | NPC1RAB9ATTRCASP3SENP8 | |
| SCHEMBL7692389 | 0.76 | MAPT (0.49) | NPC1RAB9AMAOAAKR1C3KDM4E | |
| Xanthone SCHEMBL27726954 | 0.75 | MAOA (0.78) | NPC1RAB9ATTRMAOAKDM4E | |
| SCHEMBL11575950 | 0.75 | MAOA (0.60) | NPC1RAB9ATTRCASP3SENP8 | |
| SCHEMBL10882826 | 0.74 | NPC1 (1.00) | NPC1RAB9ATTRCASP3SENP8 | |
| SCHEMBL1787556 | 0.72 | TTR (1.00) | NPC1RAB9ATTRMAOAKDM4E | |
| Xanthone SCHEMBL11245548 | 0.72 | MAOA (0.86) | NPC1RAB9ATTRMAOAKDM4E | |
| Xanthone SCHEMBL28434710 | 0.72 | MAOA (0.95) | NPC1RAB9ATTRMAOAKDM4E | |
| Xanthone SCHEMBL9738572 | 0.71 | NPC1 (0.73) | NPC1RAB9ATTRMAOAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6048667-A | FREE RADICALS OR CATION POLYMERIZABLE OR PHOTOCROSSLINKABLE MONOMERS, SUBSTRATES AND PHOTOINITIATORS, BONDING WITH SUBSTRATES | CIBA SPECIALTY CHEMICALS CORP. (US) | 2000-04-11 | — | — | US | disclosed |
| EP-0839341-A1 | HETEROGENEOUS PHOTO-INITIATORS, PHOTOPOLYMERISABLE COMPOSITIONS AND THEIR USE | Ciba SC Holding AG (CH) | 1998-05-06 | — | — | EP | disclosed |
| WO-1997004361-A1 | HETEROGENEOUS PHOTO-INITIATORS, PHOTOPOLYMERISABLE COMPOSITIONS AND THEIR USE | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 1997-02-06 | — | — | WO | disclosed |