Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.64 |
| ▸ | CTSS | P25774 | 4/20 | 0.64 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KLK7 | P49862 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13778725 | 1.00 | CTSK (0.64) | CTSKCTSSCA2TSHREPHX2 | |
| SCHEMBL15081482 | 1.00 | CTSK (0.64) | CTSKCTSSCA2TSHREPHX2 | |
| SCHEMBL6623782 | 0.89 | CTSK (0.63) | CTSKCTSSCA2TSHREPHX2 | |
| SCHEMBL6623780 | 0.89 | CTSK (0.63) | CTSKCTSSCA2TSHREPHX2 | |
| SCHEMBL5717952 | 0.89 | CTSK (0.63) | CTSKCTSSCA2TSHREPHX2 | |
| SCHEMBL17326876 | 0.88 | CTSS (0.56) | CTSKCTSSCA2 | |
| SCHEMBL352156 | 0.87 | CTSS (0.68) | CTSKCTSSCA2TSHREPHX2 | |
| SCHEMBL478905 | 0.87 | CTSS (0.68) | CTSKCTSSCA2TSHREPHX2 | |
| SCHEMBL4395744 | 0.87 | CTSS (0.68) | CTSKCTSSCA2TSHREPHX2 | |
| SCHEMBL27704332 | 0.87 | CTSK (0.64) | CTSKCTSSCA2TSHREPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015140481-A1 | ANTIMICROBIAL COMPOUNDS | bioMérieux (FR) | 2015-09-24 | — | — | WO | disclosed |
| EP-1054865-A1 | FARNESYL TRANSFERASE INHIBITORS | AstraZeneca UK Limited (GB) | 2000-11-29 | — | — | EP | disclosed |
| WO-1999041235-A1 | FARNESYL TRANSFERASE INHIBITORS | ASTRAZENECA UK LIMITED (GB) | 1999-08-19 | — | — | WO | disclosed |