Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GCGR | P47871 | 1/20 | 0.41 |
| ▸ | GIPR | P48546 | 1/20 | 0.41 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8198550 | 0.85 | MLYCD (0.46) | MLYCDNAMPTTRPV1DHODHGCGR | |
| SCHEMBL8203614 | 0.84 | TAOK1 (0.45) | MLYCDNAMPTTAOK3 | |
| SCHEMBL8203404 | 0.77 | ALDH1A1 (0.50) | MEN1KMT2ANPC1RAB9AL3MBTL1 | |
| SCHEMBL24495850 | 0.73 | SMN1; SMN2 (0.62) | MLYCDNAMPTKMT2AL3MBTL1LMNA | |
| SCHEMBL8203558 | 0.73 | MLYCD (0.48) | MLYCDNAMPTKMT2ANPC1RAB9A | |
| SCHEMBL8589013 | 0.70 | MLYCD (0.45) | MLYCDNAMPTKMT2ANPC1RAB9A | |
| SCHEMBL8589012 | 0.70 | MLYCD (0.45) | MLYCDNAMPTKMT2ANPC1RAB9A | |
| SCHEMBL17865780 | 0.70 | MLYCD (0.77) | MLYCDNAMPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL14029670 | 0.68 | CHRNB2 (0.39) | DHODHMEN1KMT2ANPC1RAB9A | |
| SCHEMBL10246936 | 0.68 | TAOK3 (0.52) | DHODHMEN1KMT2ATAOK3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998036749-A1 | TETRALONE DERIVATIVES AS ANTIARRHYTHMIC AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-08-27 | — | — | WO | claimed |
| US-6048877-A | Tetralone derivatives as antiarrhythmic agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-04-11 | — | — | US | disclosed |
| WO-1998036749-A1 | TETRALONE DERIVATIVES AS ANTIARRHYTHMIC AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-08-27 | — | — | WO | disclosed |