Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.65 |
| ▸ | MEN1 | O00255 | 7/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | THRB | P10828 | 3/20 | 0.65 |
| ▸ | POLB | P06746 | 3/20 | 0.65 |
| ▸ | RECQL | P46063 | 2/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | MMP14 | P50281 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2839419 | 0.79 | MAPT (1.00) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| Hydrochloric Acid SCHEMBL11043762 | 0.78 | MAPT (0.97) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL11294919 | 0.77 | MAOA (0.49) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL68628 | 0.77 | MAPT (0.68) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL11411791 | 0.77 | FTO (0.73) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL3453760 | 0.76 | MAPT (0.66) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL8635199 | 0.76 | MAPT (0.66) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL8040040 | 0.76 | ALDH1A1 (0.74) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL29568790 | 0.75 | MAPT (0.74) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL71118 | 0.75 | MAPT (0.74) | MAPTALDH1A1MEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736039-B1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK AS (DK) | 2000-10-25 | — | — | EP | disclosed |
| US-5767085-A | PEPTIDE DERIVATIVES | NOVO NORDISK A/S (DK) | 1998-06-16 | — | — | US | disclosed |
| EP-0736039-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1996-10-09 | — | — | EP | disclosed |
| WO-1995017423-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1995-06-29 | — | — | WO | disclosed |