Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.70 |
| ▸ | FLT1 | P17948 | 1/20 | 0.55 |
| ▸ | FLT4 | P35916 | 1/20 | 0.55 |
| ▸ | KDR | P35968 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8208503 | 0.86 | FADS1 (0.56) | ABL1ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL8639956 | 0.84 | ALDH1A1 (0.66) | ABL1FLT1FLT4KDRALDH1A1 | |
| SCHEMBL144920 | 0.82 | ABL1 (0.64) | ABL1FLT1FLT4KDRALDH1A1 | |
| SCHEMBL771687 | 0.82 | ABL1 (1.00) | ABL1FLT1FLT4KDRALDH1A1 | |
| SCHEMBL11134938 | 0.81 | ABL1 (0.63) | ABL1FLT1FLT4KDRALDH1A1 | |
| SCHEMBL3960903 | 0.80 | ABL1 (0.61) | ABL1FLT1FLT4KDRALDH1A1 | |
| SCHEMBL10705838 | 0.80 | KDM4E (0.70) | ABL1FLT1FLT4KDRALDH1A1 | |
| SCHEMBL1559630 | 0.79 | HDAC1 (0.46) | ABL1ALDH1A1KDM4EMAPTGAA | |
| SCHEMBL13181147 | 0.78 | LMNA (0.59) | ABL1FLT1FLT4KDRALDH1A1 | |
| SCHEMBL13152444 | 0.78 | ABL1 (0.58) | ABL1FLT1FLT4KDRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0979227-A1 | 4,1-BENZOXAZEPINES, THEIR ANALOGUES, AND THEIR USE AS SOMATOSTATIN AGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2000-02-16 | — | — | EP | disclosed |
| WO-1998047882-A1 | 4,1-BENZOXAZEPINES, THEIR ANALOGUES, AND THEIR USE AS SOMATOSTATIN AGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-10-29 | — | — | WO | disclosed |