Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FADS1 | O60427 | 2/20 | 0.56 |
| ▸ | ABL1 | P00519 | 1/20 | 0.56 |
| ▸ | GCK | P35557 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | NOS2 | P35228 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | BRAF | P15056 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8205593 | 0.86 | ABL1 (0.70) | FADS1ABL1ALDH1A1LMNAKDM4E | |
| SCHEMBL140037 | 0.82 | FADS1 (0.59) | FADS1ABL1GCKRECQLNOS2 | |
| SCHEMBL267531 | 0.82 | ABL1 (0.74) | FADS1ABL1RECQLNOS2ALDH1A1 | |
| SCHEMBL13761455 | 0.81 | FADS1 (0.55) | FADS1ABL1GCKRECQLNOS2 | |
| SCHEMBL8639956 | 0.81 | ALDH1A1 (0.66) | ABL1RECQLALDH1A1LMNAKDM4E | |
| SCHEMBL3637360 | 0.80 | FADS1 (0.61) | FADS1ABL1GCKRECQLNOS2 | |
| SCHEMBL1095186 | 0.80 | ALDH1A1 (0.70) | FADS1ABL1GCKRECQLNOS2 | |
| SCHEMBL28903979 | 0.80 | LMNA (0.50) | ABL1RECQLALDH1A1LMNAKDM4E | |
| SCHEMBL15284054 | 0.79 | KDM4E (0.58) | RECQLALDH1A1KDM4ENPC1HDAC1 | |
| SCHEMBL8199077 | 0.79 | BRAF (0.51) | RECQLNOS2ALDH1A1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0979227-A1 | 4,1-BENZOXAZEPINES, THEIR ANALOGUES, AND THEIR USE AS SOMATOSTATIN AGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2000-02-16 | — | — | EP | disclosed |
| WO-1998047882-A1 | 4,1-BENZOXAZEPINES, THEIR ANALOGUES, AND THEIR USE AS SOMATOSTATIN AGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-10-29 | — | — | WO | disclosed |