Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | GFER | P55789 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | TYK2 | P29597 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RORC | P51449 | 2/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8212669 | 0.89 | MAPT (0.46) | MAPTKMT2AMEN1HSD17B10SMN1; SMN2 | |
| SCHEMBL28582515 | 0.83 | ALDH1A1 (0.67) | MAPTKMT2AMEN1HSD17B10SMN1; SMN2 | |
| SCHEMBL25395048 | 0.82 | MAPT (0.66) | MAPTKMT2AMEN1HSD17B10SMN1; SMN2 | |
| SCHEMBL22089468 | 0.81 | MEN1 (0.60) | MAPTKMT2AMEN1HSD17B10SMN1; SMN2 | |
| SCHEMBL8213832 | 0.81 | HSD17B10 (0.53) | MAPTKMT2AMEN1HSD17B10SMN1; SMN2 | |
| SCHEMBL18147101 | 0.81 | MEN1 (0.52) | MAPTKMT2AMEN1HSD17B10SMN1; SMN2 | |
| SCHEMBL18146154 | 0.80 | CYP1A2 (0.68) | MAPTKMT2AMEN1HSD17B10SMN1; SMN2 | |
| SCHEMBL8054228 | 0.79 | SMN1; SMN2 (0.67) | MAPTKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8212323 | 0.78 | RORC (0.53) | MAPTKMT2AMEN1SMN1; SMN2GFER | |
| SCHEMBL29617476 | 0.78 | KCNMA1 (0.68) | MAPTKMT2AMEN1HSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021088-A2 | SALICYLANILIDES ENHANCE ORAL DELIVERY OF THERAPEUTIC PEPTIDES | THE REGENTS OF THE UNIVERSITY OF CALIFORNINA (US) | 2008-02-21 | — | — | WO | disclosed |