Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8205901 | 0.89 | MAPT (0.57) | MAPTKMT2AMEN1HSD17B10SMN1; SMN2 | |
| SCHEMBL8053240 | 0.80 | RORC (0.61) | MAPTKMT2AMEN1SMN1; SMN2RAB9A | |
| SCHEMBL8213832 | 0.76 | HSD17B10 (0.53) | MAPTKMT2AMEN1HSD17B10SMN1; SMN2 | |
| SCHEMBL28582515 | 0.76 | ALDH1A1 (0.67) | MAPTKMT2AMEN1HSD17B10SMN1; SMN2 | |
| SCHEMBL8212323 | 0.74 | RORC (0.53) | MAPTKMT2AMEN1SMN1; SMN2RAB9A | |
| SCHEMBL18147101 | 0.73 | MEN1 (0.52) | MAPTKMT2AMEN1HSD17B10SMN1; SMN2 | |
| SCHEMBL8216234 | 0.73 | JAK2 (0.49) | MAPTKMT2AMEN1HSD17B10SMN1; SMN2 | |
| SCHEMBL11573737 | 0.73 | CA1 (0.63) | MAPTHSD17B10SMN1; SMN2RAB9AKDM4E | |
| SCHEMBL18146154 | 0.73 | CYP1A2 (0.68) | MAPTKMT2AMEN1HSD17B10SMN1; SMN2 | |
| SCHEMBL10597000 | 0.72 | RAB9A (0.59) | MAPTKMT2AMEN1HSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021088-A2 | SALICYLANILIDES ENHANCE ORAL DELIVERY OF THERAPEUTIC PEPTIDES | THE REGENTS OF THE UNIVERSITY OF CALIFORNINA (US) | 2008-02-21 | — | — | WO | disclosed |