Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | JAK2 | O60674 | 1/20 | 0.52 |
| ▸ | TYK2 | P29597 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PYGL | P06737 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8216234 | 0.85 | JAK2 (0.49) | HSD17B10JAK2TYK2MAPTMEN1 | |
| SCHEMBL15668350 | 0.82 | CYP1A2 (0.68) | HSD17B10MAPK1MAPTMEN1KMT2A | |
| SCHEMBL25395048 | 0.81 | MAPT (0.66) | HSD17B10MAPK1JAK2TYK2HDAC8 | |
| SCHEMBL8205901 | 0.81 | MAPT (0.57) | HSD17B10MAPK1JAK2TYK2MAPT | |
| SCHEMBL8053996 | 0.78 | SMN1; SMN2 (0.64) | MAPK1JAK2MAPTMEN1KMT2A | |
| SCHEMBL8218122 | 0.77 | HSD17B10 (0.54) | HSD17B10MAPK1HDAC8HDAC6HDAC1 | |
| SCHEMBL8216235 | 0.77 | ALDH1A1 (0.47) | HSD17B10JAK2TYK2HDAC1MAPT | |
| SCHEMBL8212669 | 0.76 | MAPT (0.46) | HSD17B10MAPK1JAK2TYK2MAPT | |
| SCHEMBL11219138 | 0.76 | RAB9A (0.67) | HSD17B10JAK2TYK2HDAC8HDAC6 | |
| SCHEMBL29459607 | 0.76 | RAB9A (0.67) | HSD17B10JAK2TYK2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021088-A2 | SALICYLANILIDES ENHANCE ORAL DELIVERY OF THERAPEUTIC PEPTIDES | THE REGENTS OF THE UNIVERSITY OF CALIFORNINA (US) | 2008-02-21 | — | — | WO | disclosed |