Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 5/20 | 0.40 |
| ▸ | GALR1 | P47211 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 3/20 | 0.36 |
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8212891 | 0.95 | ALDH1A1 (0.40) | ALOX15GALR1CNR1CNR2KDM4E | |
| SCHEMBL8207229 | 0.92 | ALOX15 (0.40) | ALOX15GALR1CNR1CNR2ALDH1A1 | |
| SCHEMBL8209525 | 0.87 | KMT2A (0.37) | ALOX15ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL8199872 | 0.85 | TAAR1 (0.44) | ALOX15GALR1ALDH1A1HPGDKMT2A | |
| SCHEMBL8211806 | 0.85 | PYGL (0.36) | ALDH1A1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL8206045 | 0.84 | GRIN2C (0.39) | GALR1KDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL8199938 | 0.82 | ALDH1A1 (0.38) | GALR1KDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL8206226 | 0.80 | ALDH1A1 (0.42) | ALOX15KDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL8200375 | 0.78 | ALDH1A1 (0.41) | ALOX15CNR1CNR2KDM4EALDH1A1 | |
| SCHEMBL8207755 | 0.76 | GRIN2C (0.48) | KDM4EALDH1A1HPGDKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143777-A | ENZYME INHIBITORS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-11-07 | — | — | US | disclosed |