Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 3/20 | 0.38 |
| ▸ | FNTA | P49354 | 3/20 | 0.37 |
| ▸ | FNTB | P49356 | 3/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | ACKR3 | P25106 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8199055 | 0.92 | AGTR2 (0.43) | AGTR2JAK2JAK1ACKR3MEN1 | |
| SCHEMBL8207012 | 0.89 | KDM4E (0.47) | AGTR2FNTAFNTBALDH1A1OPRM1 | |
| SCHEMBL8206924 | 0.86 | AGTR2 (0.43) | AGTR2JAK2JAK1ALDH1A1KMT2A | |
| SCHEMBL8206102 | 0.84 | MCHR1 (0.41) | AGTR2ACKR3ALDH1A1CHRM3CHRM2 | |
| SCHEMBL8206641 | 0.83 | SLC6A4 (0.40) | AGTR2JAK2JAK1ALDH1A1HTT | |
| SCHEMBL8199247 | 0.81 | AGTR2 (0.42) | AGTR2OPRM1SIGMAR1CHRM3CHRM2 | |
| SCHEMBL8207101 | 0.81 | CHRM2 (0.46) | MEN1ALDH1A1KMT2AOPRM1SIGMAR1 | |
| SCHEMBL8206406 | 0.80 | UBE2M (0.40) | ACKR3MEN1ALDH1A1KMT2AOPRM1 | |
| SCHEMBL8206842 | 0.79 | MAPT (0.36) | ACKR3ALDH1A1GAAHTTKCNH2 | |
| Hydrochloric Acid SCHEMBL8209836 | 0.79 | AGTR2 (0.47) | AGTR2OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0999205-A1 | AMINOCYCLOALKANE COMPOUNDS | Mitsubishi-Tokyo Pharmaceuticals, Inc. (JP) | 2000-05-10 | — | — | EP | disclosed |