Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.39 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.39 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8199055 | 0.88 | AGTR2 (0.43) | CHRM2CHRM1CHRM3KMT2AMEN1 | |
| SCHEMBL8206641 | 0.87 | SLC6A4 (0.40) | CHRM2CHRM1CHRM3ALDH1A1GRM2 | |
| SCHEMBL8206924 | 0.82 | AGTR2 (0.43) | CHRM2CHRM1CHRM3KMT2AALDH1A1 | |
| SCHEMBL8205282 | 0.82 | CHRM3 (0.45) | CHRM2CHRM1CHRM3ALOX5OPRM1 | |
| SCHEMBL8206397 | 0.81 | AGTR2 (0.38) | CHRM2CHRM1CHRM3KMT2AMEN1 | |
| SCHEMBL8207012 | 0.80 | KDM4E (0.47) | CHRM2CHRM1CHRM3ALDH1A1GRM2 | |
| SCHEMBL8207099 | 0.80 | KDM4E (0.46) | CHRM2CHRM1CHRM3KMT2AMEN1 | |
| SCHEMBL8199247 | 0.79 | AGTR2 (0.42) | CHRM2CHRM1CHRM3OPRM1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL8209836 | 0.77 | AGTR2 (0.47) | ALOX5OPRM1 | |
| SCHEMBL8208772 | 0.77 | CHRM3 (0.45) | CHRM2CHRM1CHRM3ALOX5OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0999205-A1 | AMINOCYCLOALKANE COMPOUNDS | Mitsubishi-Tokyo Pharmaceuticals, Inc. (JP) | 2000-05-10 | — | — | EP | disclosed |