Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PKLR | P30613 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 6/20 | 0.46 |
| ▸ | MMP3 | P08254 | 6/20 | 0.46 |
| ▸ | MMP7 | P09237 | 4/20 | 0.46 |
| ▸ | MMP13 | P45452 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8199769 | 0.84 | MMP3 (0.50) | MMP2MMP1MMP3MMP7MMP13 | |
| SCHEMBL8206196 | 0.78 | MMP8 (0.62) | MMP2MMP1MMP3MMP7MMP13 | |
| SCHEMBL8211439 | 0.77 | LMNA (0.55) | NPC1PKMPKLRRAB9AMMP1 | |
| SCHEMBL8206472 | 0.77 | LMNA (0.55) | NPC1PKMPKLRRAB9AMMP1 | |
| SCHEMBL8206912 | 0.76 | MMP1 (0.58) | MMP2NPC1PKMPKLRRAB9A | |
| SCHEMBL8207818 | 0.68 | PKM (0.66) | MMP2NPC1PKMPKLRRAB9A | |
| SCHEMBL1795644 | 0.67 | ALDH1A1 (0.71) | NPC1PKMPKLRRAB9AHSD11B1 | |
| SCHEMBL20198697 | 0.67 | TAS2R14 (0.61) | MMP1MMP3MMP13LMNATSHR | |
| SCHEMBL8207819 | 0.67 | MMP1 (0.59) | MMP2NPC1PKMPKLRRAB9A | |
| SCHEMBL8207637 | 0.67 | SMN1; SMN2 (0.59) | NPC1PKMPKLRRAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6121272-A | Bidentate metalloprotease inhibitors | THE PROCTER & GAMBLE COMPANY (US) | 2000-09-19 | — | — | US | disclosed |